Preparation Process of Dehydrodiisoeugenol in Myristica fragrans

WANG Cong1; MENG Xiao-wei1; LIU Yong-gang1; ZHANG Jian-wei2; ZHANG Hong-gui1

doi:10.13422/j.cnki.syfjx.2012.04.028

您当前的位置：

首页 >

文章列表页 >

Preparation Process of Dehydrodiisoeugenol in Myristica fragrans

更新时间：2024-09-23

- Preparation Process of Dehydrodiisoeugenol in Myristica fragrans
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 4, Pages: 74-78(2012)
- 作者机构：
  
  1. 北京中医药大学中药学院
  2. 首都医科大学化学生物学及药学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2012.04.028
  CLC： R284.1
- Published：2012
- 稿件说明：
移动端阅览
[1]王聪,孟晓伟,刘永刚,张建伟,张宏桂.肉豆蔻对照品去氢二异丁香酚制备工艺[J].中国实验方剂学杂志,2012,18(04):74-78.

WANG Cong1, MENG Xiao-wei1, LIU Yong-gang1, et al. Preparation Process of Dehydrodiisoeugenol in Myristica fragrans[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(4): 74-78.
[1]王聪,孟晓伟,刘永刚,张建伟,张宏桂.肉豆蔻对照品去氢二异丁香酚制备工艺[J].中国实验方剂学杂志,2012,18(04):74-78. DOI： 10.13422/j.cnki.syfjx.2012.04.028.

WANG Cong1, MENG Xiao-wei1, LIU Yong-gang1, et al. Preparation Process of Dehydrodiisoeugenol in Myristica fragrans[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(4): 74-78. DOI： 10.13422/j.cnki.syfjx.2012.04.028.

摘要

目的:优化制备去氢二异丁香酚中药化学对照品的工艺。方法:以去氢二异丁香酚提取率为考察指标

在单因素试验的基础上

通过L9（34）正交试验确定最佳提取条件并放大到中试量。结果:采用80%乙醇

料液比10∶1回流提取药材2次

每次2 h

提取物经无水乙醇、乙酸乙酯萃取后

经硅胶柱层析、重结晶

获得9 g对照品。结论:本工艺高效、简便、低成本

适用于去氢二异丁香酚对照品的制备。

Abstract

Objective:To optimize the process of preparing dehydrodiisoeugenol chemical reference substance.Method:Taking extract rate of dehydrodiisoeugenol as index

the best extraction condition of dehydrodiisoeug-enol was determined by single factor test and orthogonal test L9（34）

which was scaled up to pilot volume.Result:Raw material was extracted with 80% ethanol at a 10∶1 solid-liquid ratio for twice and 2 h each time

the yielded extract was first seperated by extraction with absolute ethyl alcohol、acetyl acetate.Afer this

by the methods of silicagel column chromatography and recrystallization we produce 9 g of reference substance was producued.Conclusion:The process is effective

simple and economic

and can meet the need of gram-size preparation.

关键词

Keywords

references

Views

209

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Determination of Dehydrodiisoeugenol in Nutmeg Roasted with Wheat Bran by RP-HPLC

Determination of Total Lignans in and . Roasted with Wheat Bran

Quality Standard for Ershiwei Roudoukou Pills

HPLC Characteristic Fingerprint of Jiagasong Decoction

Related Author

ZHANG Hong-gui

ZHANG Jian-wei

LIU Yong-gang

MENG Xiao-wei

WANG Cong

JIA Tian-zhu

CHEN Jian-feng

YUAN Zi-min

Related Institution

No data

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰