LIU Jun-dong1, YE Zheng-liang2, LI De-kun2, et al. Rapid Determination of Moisture Content in Danshen Polyphenols Acid Injection with Near-infrared Diffused Reflection Spectroscopy[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(4): 91-94.
LIU Jun-dong1, YE Zheng-liang2, LI De-kun2, et al. Rapid Determination of Moisture Content in Danshen Polyphenols Acid Injection with Near-infrared Diffused Reflection Spectroscopy[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(4): 91-94. DOI: 10.13422/j.cnki.syfjx.2012.04.033.
Rapid Determination of Moisture Content in Danshen Polyphenols Acid Injection with Near-infrared Diffused Reflection Spectroscopy
Objective:A near-infrared(NIR) quantitative method was developed for rapid and nondestructive determination of moisture content in Danshen polyphenols acid injection.Method:The diffuse reflectance near-infrared spectra of Danshen polyphenols injection were measured intact by a fiber optic probe.The quantitative calibration model was developed using partial least squares(PLS) algorithm.Result:Using 53 samples Near-infrared spectra were pretreated with the second Derivative.The wavebands containing 11 993.1-6 098.8 cm-1 and 5 450.7-4 598.2 cm-1were selected
established and the quantitative calibration model of moisture content in Danshen polyphenols injection was established.The results shows that R2was 0.991 1
root mean square errors of Cross-Validation(RMSECV) was 0.210 and the best dimension was 4.10 samples as validation set
the RMSEP was 0.243.Conclusion:The presented method is timesaving
convenient and accuracy
which could be applied for rapidly determining moisture content in large numbers of samples.It is valuables for us to research the quality of traditional Chinese medical preparations.
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Related Author
LIU Jun-dong
YE Zheng-liang
LI De-kun
YUE Hong-shui
ZHOU Da-zheng
Xing LEI
Fang WANG
Ming YANG
Related Institution
Key Laboratory of Modern Preparation of Traditional Chinese Medicine,Ministry of Education,Jiangxi University of Chinese Medicine
College of Pharmacy, Shaanxi University of Chinese Medicine
College Pharmacy, Chengdu University of Traditional Chinese Medicine(TCM)