LIU Li-na, SUN Lei, CHENG Xian-long, et al. Identification of Matrine and Ammothamnine in Picrasmae Lignum by High Performance Liqid Chromatography /Tandem Mass spectromety[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(4): 110-113.
LIU Li-na, SUN Lei, CHENG Xian-long, et al. Identification of Matrine and Ammothamnine in Picrasmae Lignum by High Performance Liqid Chromatography /Tandem Mass spectromety[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(4): 110-113. DOI: 10.13422/j.cnki.syfjx.2012.04.038.
Identification of Matrine and Ammothamnine in Picrasmae Lignum by High Performance Liqid Chromatography /Tandem Mass spectromety
Objective:Identification of matrine and ammothamnine in picrasmae lignum by high performance liqid chromatography /Tandem Mass spectrometry.Method:Two alkaloids in picrasmae lignum were ananlyzed by HPLC-ESI /Q-TOF MS /MS.According to the accurate molecular weight
retention time and MSn data by compared with reference substances
the chemical structures were identified.After that
quantitative method was built based on the techniques of LC-Q-Q-Q.Result:Two trace components were identified in picrasmae lignum.The method is specific
sensitive and can be used as the identification of matrine and oxymatrine in picrasmae lignum.Conclusion:It was the first time to report the identification of Matrine and ammothamnine in picrasmae lignum by LC-MS.The content of matrine and ammothamnine in picrasmae lignum vary greatly with the different part and the area of produce.
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Related Author
LIU Li-na
SUN Lei
CHENG Xian-long
TIAN Jin-gai
JIN Hong-yu
WU Xiao-yan
TANG Ai-cun
XIE Zhen
Related Institution
Beijing Key Laboratory of Traditional Chinese Medicine(TCM) Quality Evaluation, Beijing University of Chinese Medicine
School of TCM, Beijing University of Chinese Medicine
National Engineering Laboratory for Quality Control Technology of Chinese Materia Medica, Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences
Medicinal College, Guangxi University
Jilin Natural Pharmaceutical Research and Development Co.Ltd.