LIU Shu-yang1, FENG Wei-hong2, DU Mao-bo2, et al. In vitro Releasing Property of Shuangqin Eye Gel[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(8): 9-11.
LIU Shu-yang1, FENG Wei-hong2, DU Mao-bo2, et al. In vitro Releasing Property of Shuangqin Eye Gel[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(8): 9-11. DOI: 10.13422/j.cnki.syfjx.2012.08.030.
Objective:To study on in vivo releasing characteristics of Shuangqin eye gel.Method: The content of aesculin was determined by HPLC
which was used as index;Modified Franz diffusion cell method was applied to investigate in vitro release characteristics of Shuangqin eye gel with semi-permeable membrane as a barrier.Result: Aesculin in Shuangqin eye gel released fitted well with first order model
fitting equation of it:Y=-1.258 8 X-0.816 2(r=0.999 2).Conclusion: Release of Shuangqin eye gel was non-Fick diffusion.