TAO Yi, SHEN Tao, MA Hui. Comparison on Efficacy of Rehmanniae Radix Praeparata and its Paired Medicines for Treatment of Diabetic Osteoporosis in Rats[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(8): 249-251.
TAO Yi, SHEN Tao, MA Hui. Comparison on Efficacy of Rehmanniae Radix Praeparata and its Paired Medicines for Treatment of Diabetic Osteoporosis in Rats[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(8): 249-251. DOI: 10.13422/j.cnki.syfjx.2012.08.084.
Comparison on Efficacy of Rehmanniae Radix Praeparata and its Paired Medicines for Treatment of Diabetic Osteoporosis in Rats
Objective:To study the Rehmanniae Radix Praeparata(RRP) and its paired medicines on bone metabolism in rats with diabetes.Method: Alloxan intraperitoneal injection was applied for establishing rat model of diabetes mellitus
according to blood glucose levels the rats were randomly divided into 7 groups
and then RRP and its paired medicines were used for treatment.Serum insulin
bone density
bone metabolism biochemical index were observed.Result: RRP and its paired medicines showed obvious regulating effect on bone metabolism.RRP and RRP+Herba Epimedii appeared to be the best.Conclusion: The different compatibility of RRP has different efficacy for prevention and treatment in diabetic rats with osteoporosis.