ZHAO Yu-wei1, YU Miao1, HE Li2, et al. Optimization of Extraction Process for Zidianling Granule[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 32-35.
ZHAO Yu-wei1, YU Miao1, HE Li2, et al. Optimization of Extraction Process for Zidianling Granule[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 32-35. DOI: 10.13422/j.cnki.syfjx.2012.09.006.
Optimization of Extraction Process for Zidianling Granule
Objective:To optimize extraction technology of Zidianling granule.Method:With baicalin and matrine as indicators
main factors of extraction process were optimized by L9(34)orthogonal test
the content of baicalin and matrine were determined by HPLC.Result:Optimum extraction process was determined as follows: Scutellaria baicalensis and other five herbs was extracted 2 times with 6 times the amount of 70% ethanol
1 hour each time;Residues of above mentioned drugs and the others herbs(Bubalus bubalis and the others herbs) were extracted 3 times with 10 times the amount of wate
1.5 h each time.Conclusion:This optimized technology for Zidianling granules was economic
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Related Author
ZHAO Yu-wei
YU Miao
HE Li
HE Zhong-mei
YUAN Yuan
SUN Yu-bin
RAO Xiao-yong
HE Shuang-feng
Related Institution
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences
上海中医药大学中药现代制剂技术教育部工程研究中心
Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine
Beijing Key Laboratory of Protection and Utilization of Traditional Chinese Medicine Resources,Beijing Normal University
College of Pharmacy,Nanjing University of Chinese Medicine