QIN Chao, RONG Rong, YANG Yong, et al. Optimization of Extraction Technology for Mahuang Fuzi Xixin Decoction by Multi-index Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 35-39.
QIN Chao, RONG Rong, YANG Yong, et al. Optimization of Extraction Technology for Mahuang Fuzi Xixin Decoction by Multi-index Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 35-39. DOI: 10.13422/j.cnki.syfjx.2012.09.007.
Optimization of Extraction Technology for Mahuang Fuzi Xixin Decoction by Multi-index Orthogonal Test
Objective:To optimize extraction technology of Mahuang Fuzi Xixin decoction.Method:With ephedrine
pseudoephedrine
benzoyl aconine
benzoyl mesaconitine
benzoyl hypaconitine and yield of extract as indexes
the content of these were determined by HPLC
effect of extraction time
extraction times and the amount of solvents on extraction technology was investigated by L9(3)4 orthogonal test.Result:Optimum extraction conditions were:extracted 2 times with 16 times the amount of hydrochloric acid(pH 2.0) with 2.5 hours each time.Conclusion:It was more suitable for integral view of Chinese medicine by multi-index comprehensive evaluation method
this optimized extraction technology was reasonable