ZHANG Hai-yan1, WU Wei-kui1, LU Qian1, et al. Effect of Borneol on Promoting Absorption of Oral Drugs[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 294-297.
ZHANG Hai-yan1, WU Wei-kui1, LU Qian1, et al. Effect of Borneol on Promoting Absorption of Oral Drugs[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 294-297. DOI: 10.13422/j.cnki.syfjx.2012.09.057.
Effect of Borneol on Promoting Absorption of Oral Drugs
Literatures about promoting absorption of oral drugs by borneol are analyzed.It is usual that the oral bioavailability is poor.Appling a safe and effective absorption enhancer to increase oral bioavailability is becoming a focus.This paper mainly reviews three methods about promoting absorption of oral drugs(in situ
in vitro and in vivo).Research showed that the effect of borneol on regulating the absorption of oral drugs was related to the drug structure and concentration
species
concentration and usage of borneol
but the mechanism of absorption is uncertain.Therefore
for the drugs of poor bioavailability of poor solubility and rapid metabolism
the development status of borneol will provide references for further research on borneol promoting absorption.
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Related Author
ZHANG Hai-yan
WU Wei-kui
LU Qian
HE Ya
SONG Wei
LI Fang
YANG Ming
LI Xi
Related Institution
Wuya College of Innovation,Shenyang Pharmaceutical University
Suzhou Youseen New Drug Research&Development Co. Ltd.
School of Pharmacy,Soochow University
School of Chinese Materia Medica,Shanghai University of Traditional Chinese Medicine
Affiliated Hospital of Nanjing University of Chinese Medicine