Dissolution Rate of Raw and Processed Products of Gypsum Calcite in Artificial Intestinal Fluid and Gastric Juice

LU Jing-kun; CHEN Zhao-jun; ZHOU Hao-fei; LIU Zhi-jie; YI He

doi:10.13422/j.cnki.syfjx.2012.09.060

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Dissolution Rate of Raw and Processed Products of Gypsum Calcite in Artificial Intestinal Fluid and Gastric Juice

更新时间：2024-09-23

- Dissolution Rate of Raw and Processed Products of Gypsum Calcite in Artificial Intestinal Fluid and Gastric Juice
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 9, Pages: 23-25(2012)
- 作者机构：
  
  内蒙古医学院药学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2012.09.060
  CLC： R283.6
- Published：2012
- 稿件说明：
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[1]陆景坤,陈朝军,周昊菲,刘智杰,毅和.寒水石生品、炮制品在人工胃肠液中的溶出率[J].中国实验方剂学杂志,2012,18(09):23-25.

LU Jing-kun, CHEN Zhao-jun, ZHOU Hao-fei, et al. Dissolution Rate of Raw and Processed Products of Gypsum Calcite in Artificial Intestinal Fluid and Gastric Juice[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 23-25.
[1]陆景坤,陈朝军,周昊菲,刘智杰,毅和.寒水石生品、炮制品在人工胃肠液中的溶出率[J].中国实验方剂学杂志,2012,18(09):23-25. DOI： 10.13422/j.cnki.syfjx.2012.09.060.

LU Jing-kun, CHEN Zhao-jun, ZHOU Hao-fei, et al. Dissolution Rate of Raw and Processed Products of Gypsum Calcite in Artificial Intestinal Fluid and Gastric Juice[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 23-25. DOI： 10.13422/j.cnki.syfjx.2012.09.060.

摘要

目的:对南、北寒水石奶淬、水淬、生品在人工胃肠液中溶出率进行分析。方法:通过人工模拟胃肠环境来分析寒水石的溶出情况

利用配位滴定法检测样品中主成分钙含量

计算溶出率。结果:南、北寒水石在人工胃液中溶出率在70%～110%

溶出率依次为奶淬<水淬<生品;在人工肠液中

南寒水石溶出率低于10%

其中生品溶出率最低

北寒水石低于20%

水淬制品溶出率最低。结论:南、北寒水石可能主要在胃内吸收

肠内吸收较少。

Abstract

Objective:To analyze dissolution ratio of milk quenching product

water quenching product and raw materials of Gypsum and Calcite in artificial intestinal fluid and gastric juice.Method:Dissolution rate of Calcium were analyzed in artificial gastrointestinal environment

to calculate dissolution ratio with detected the content of principal component（calcium） by coordination titration.Result:Dissolution ratio of Gypsum and Calcite in artificial gastric juice were between 70% and 110%

order of dissolution rate were:milk quenching<water quenching<raw materials.In artificial intestinal fluid

dissolution rate of Calcite was less than 10%

dissolution ratio of raw materials was the lowest

while dissolution rate of Gypsum was less than 20%

the lowest one was water quenching products.Conclusion:Gypsum and Calcite might be mainly absorbed in stomach

and it was lower in the intestinal.

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Related Author

LU Jing-kun

CHEN Zhao-jun

ZHOU Hao-fei

LIU Zhi-jie

YI He

QUAN Zheng-xiang

DU Yu-zhi

WEI Li-xin

Related Institution

State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs，National Resource Center for Chinese Materia Medica，China Academy of Chinese Medical Sciences

Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica， Guangxi University of Chinese Medicine

Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules in Enterprises，Guangdong Efong Pharmaceutical Co. Ltd.

Shandong University of Traditional Chinese Medicine

Shandong Academy of Chinese Medicine

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