Antioxidative Activity of Alcoholic Extracts from Riadix Asparag

LI Yan-ju1; DU Hao2; LI Qin-shan3; LIU Yang4

doi:10.13422/j.cnki.syfjx.2012.15.057

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Antioxidative Activity of Alcoholic Extracts from Riadix Asparag

更新时间：2024-09-23

- Antioxidative Activity of Alcoholic Extracts from Riadix Asparag
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 15, Pages: 182-184(2012)
- 作者机构：
  
  1. 贵阳医学院附属医院血液科
  2. 河南科技大学第一附属医院骨科
  3. 北京协和医学院生化教研室
  4. 北京工业大学生命科学与生物医学工程系
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2012.15.057
  CLC： R285.5
- Published：2012
- 稿件说明：
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[1]李艳菊,杜浩,李琴山,刘洋.贵州产天冬醇提液体外氧自由基清除作用的研究[J].中国实验方剂学杂志,2012,18(15):182-184.

LI Yan-ju1, DU Hao2, LI Qin-shan3, et al. Antioxidative Activity of Alcoholic Extracts from Riadix Asparag[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(15): 182-184.
[1]李艳菊,杜浩,李琴山,刘洋.贵州产天冬醇提液体外氧自由基清除作用的研究[J].中国实验方剂学杂志,2012,18(15):182-184. DOI： 10.13422/j.cnki.syfjx.2012.15.057.

LI Yan-ju1, DU Hao2, LI Qin-shan3, et al. Antioxidative Activity of Alcoholic Extracts from Riadix Asparag[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(15): 182-184. DOI： 10.13422/j.cnki.syfjx.2012.15.057.

摘要

目的:研究贵州产天冬醇提液体外清除羟自由基（·OH）与超氧阴离子自由基（O2-）的作用。方法:选取贵州产天冬为研究对象

采用乙醇回流提取法提取其醇提液;采用连苯三酚法在碱性溶液中自氧化反应产生超氧阴离子自由基（O2-）

采用邻二氮菲-Fe（Ⅱ）/H2O2体系产生羟自由基（·OH）

研究天冬醇提液体外清除自由基的作用;结果:贵州产天冬醇提液对O2-具有显著的清除及抑制作用（P<0.05）

而且随着药物浓度的增加

其清除及抑制作用也随之增加;贵州产天冬醇提液对·OH也有一定的清除作用（P<0.05）

其清除率为（35.1±0.16）%。结论:贵州产天冬醇提液对O2-具有显著的清除及抑制作用

对·OH也有一定的清除作用。

Abstract

Objective: To study the scavenging action of alcoholic extracts from Riadix Asparag on oxygen free radical.Method: The Asparagus ethanol-extraction liquid was estracted by ethanol refluxing extraction.Auto-oxidation in alkalcsent solution with pyrogallol can generate O2-and the system of 1

10-phenathroline-Fe（Ⅱ）/H2O2 canproduce·OH.Spectropholomemy was used to observe the effect of alcoholic extracts from Riadix Asparag upon O2-and·OH.Result:The alcoholic extracts from Riadix Asparag could decrease the levels of O2-and inhibit the generation of O2-in vitro;alcoholic extracts from Riadix Asparag could reduce the leve of ·OH（P<0.05）.Inhibition ratio is 35.1%±0.16%.Conclusion:Guizhou alcoholic extracts from Riadix Asparag could scavenge and inhibit O2-markedly and scavenge·OH as well.

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Related Institution

College of Chemistry,Chemical Engineering and Environment,Qingdao University

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