YUAN Hong-xia, WEI Cai-liu, CHENG Yao. Study on Anti-depression Effects of Xiaochaihu Tang[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(15): 190-191.
YUAN Hong-xia, WEI Cai-liu, CHENG Yao. Study on Anti-depression Effects of Xiaochaihu Tang[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(15): 190-191. DOI: 10.13422/j.cnki.syfjx.2012.15.059.
Study on Anti-depression Effects of Xiaochaihu Tang
Objective: To investigate the antidepressant action of Xiaochaihu Tang in mice.Method: Mice were randomly divided into five groups: Xiaochaihu Tang high
middle
low dose groups(orally given for 7 days
27
18
9 g·kg-1·d-1)
fluoxetine group and control group.The tail suspention test(TST)
forced swimming test(FST) were applied to evaluate antidepressant activities.Mice immobility time in forced swimming test and tail suspension test were observed.Result: Compared with the control group
the immobility time of TST and FST were shorted in Xiaochaihu Tang high
middle
low dose groups.Conclusion: Xiaochaihu Tang has certain antidepressant effect.