Optimization of Extraction Technology for Volatile Oil from Artemisia rupestris by Response Surface Methodology

YAO Xiao-yun; CHAO Qun-fang; CHEN Zhi-dan; YANG Bin-yin; WANG Gui-e

doi:10.13422/j.cnki.syfjx.2012.16.061

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Optimization of Extraction Technology for Volatile Oil from Artemisia rupestris by Response Surface Methodology

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- Optimization of Extraction Technology for Volatile Oil from Artemisia rupestris by Response Surface Methodology
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 16, Pages: 30-33(2012)
- 作者机构：
  
  新疆大学生命科学与技术学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2012.16.061
  CLC： R284.1
- Published：2012
- 稿件说明：
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[1]姚小云,晁群芳,陈志丹,杨滨银,王桂娥.响应面法优化新疆一枝蒿挥发油的提取工艺[J].中国实验方剂学杂志,2012,18(16):30-33.

YAO Xiao-yun, CHAO Qun-fang, CHEN Zhi-dan, et al. Optimization of Extraction Technology for Volatile Oil from Artemisia rupestris by Response Surface Methodology[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(16): 30-33.
[1]姚小云,晁群芳,陈志丹,杨滨银,王桂娥.响应面法优化新疆一枝蒿挥发油的提取工艺[J].中国实验方剂学杂志,2012,18(16):30-33. DOI： 10.13422/j.cnki.syfjx.2012.16.061.

YAO Xiao-yun, CHAO Qun-fang, CHEN Zhi-dan, et al. Optimization of Extraction Technology for Volatile Oil from Artemisia rupestris by Response Surface Methodology[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(16): 30-33. DOI： 10.13422/j.cnki.syfjx.2012.16.061.

摘要

目的:优选新疆一枝蒿挥发油的提取工艺条件。方法:以挥发油收率为指标

采用水蒸汽蒸馏法提取挥发油

选取药材粉碎粒径、NaCl质量分数、料液比、浸提时间为影响因素

单因素试验及响应面分析试验进行提取工艺优选。结果:最佳提取工艺条件为粉碎粒径40目

NaCl质量分数9.9%

加14.5倍量水浸提6.6 h。在此工艺条件下

新疆一枝蒿挥发油得率0.468%

结论:实测值与模型预测值相符

表明优选的工艺条件可用于新疆一枝蒿的提取。

Abstract

Objective:To optimize extraction process of volatile oil from Artemisia rupestris by response surface methodology.Method: With yield of volatile oil as indicator

volatile oil was extracted by water distillation method

single factors test and response surface methodology were used to optimize extraction technology with crushed particle size of medicinal materials

the concentration of NaCl

material-liquid ratio and extraction time as affecting factors.Result: Optimal extraction technology conditions were as follows:crushed particle size of medicinal materials 40 mesh

the concentration of NaCl 9.9%

extracted 6.6 h with 14.5 times the amount of water.Under these conditions

yield of volatile oil from A.rupestris was 0.468%.Conclusion: Measured value was agreed with model predictions

which showed that optimized extraction process could be used for extraction of A.rupestris.

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Related Author

YAO Xiao-yun

CHAO Qun-fang

CHEN Zhi-dan

YANG Bin-yin

WANG Gui-e

CHENG Dong-yan

WANG Li-shu

CHENG Dong-hong

Related Institution

Research Institute of Traditional Chinese Medicine,Heilongjiang University of Traditional Chinese Medicine

Life Science and Technology College,Heilongjiang Bayi Agricultural University

Shanghai University of Traditional Chinese Medicine

The Longhua Hospital of Shanghai University of Traditional Chinese Medicine

Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences

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