Determination of 5-Hydroxmethylfurfural in Commercial Trichosanthis Fructus by HPLC

SUN Wen; CHAO Zhi-mao; WANG Chun; WU Xiao-yi; TAN Zhi-gao

doi:10.13422/j.cnki.syfjx.2012.18.037

您当前的位置：

首页 >

文章列表页 >

Determination of 5-Hydroxmethylfurfural in Commercial Trichosanthis Fructus by HPLC

更新时间：2024-09-23

- Determination of 5-Hydroxmethylfurfural in Commercial Trichosanthis Fructus by HPLC
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 18, Pages: 73-76(2012)
- 作者机构：
  
  中国中医科学院中药研究所
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2012.18.037
  CLC： R284.1
- Published：2012
- 稿件说明：
移动端阅览
[1]孙文,巢志茂,王淳,吴晓毅,谭志高.HPLC对市售瓜蒌中5-羟甲基糠醛的含量测定[J].中国实验方剂学杂志,2012,18(18):73-76.

SUN Wen, CHAO Zhi-mao, WANG Chun, et al. Determination of 5-Hydroxmethylfurfural in Commercial Trichosanthis Fructus by HPLC[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 73-76.
[1]孙文,巢志茂,王淳,吴晓毅,谭志高.HPLC对市售瓜蒌中5-羟甲基糠醛的含量测定[J].中国实验方剂学杂志,2012,18(18):73-76. DOI： 10.13422/j.cnki.syfjx.2012.18.037.

SUN Wen, CHAO Zhi-mao, WANG Chun, et al. Determination of 5-Hydroxmethylfurfural in Commercial Trichosanthis Fructus by HPLC[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 73-76. DOI： 10.13422/j.cnki.syfjx.2012.18.037.

摘要

目的:建立常用中药瓜蒌中5-羟甲基糠醛（5-HMF）的高效液相色谱（HPLC）测定方法。方法:采用HPLC法

ODS色谱柱（4.6 mm×250 mm

5μm）

甲醇-水（15∶85）为流动相

流速0.8 mL.min-1

检测波长284 nm

柱温30℃。结果:建立了瓜蒌饮片中5-HMF的HPLC测定方法

18批市售瓜蒌样品中5-HMF的含量范围为11.10～193.6μg.g-1。结论:各地的商品瓜蒌中5-HMF的含量差异较大

该方法可作为评价瓜蒌饮片质量的指标之一。

Abstract

Objective:To establish an HPLC method for content determination of 5-hydroxymethylfurfural（5-HMF） in commercial Trichosanthis Fructus

a commonly used Chinese material medica.Method:The HPLC analysis was performed on an ODS column（4.6 mm×250 mm

5 μm） and the mobile phase consisted of methanol-water（15∶85） at a flow rate of 0.8 mL · min-1.The detective wavelength was set at 284 nm and the column temperature was maiutain at 30 ℃.Result:The HPLC method for content determination of 5-HMF in Trichosanthis Fructus was established.5-HMF was detected in 18 batches of commercial Trichosanthis Fructus

the content of which were in the range of 11.10-193.6 μg·g-1.Conclusion:The content of 5-HMF in commercial Trichosanthis Fructus is quite different.This method is suitable for the quality control of Trichosanthis Fructus.

关键词

Keywords

references

Views

388

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Determination of 5-Hydroxmethylfurfural in Commercial Trichosanthis Fructus by HPLC

HPLC Determination of Swertiajaponin in Leaves of

Study on Content Changes of Pulegone in Schizonepetae Herba under Decoction Process by HPLC Method

Simultaneous Determination of Five Components in Compound Preparation of Fuzheng Jiedu Keli by HPLC

Related Author

SUN Wen

CHAO Zhi-mao

WANG Chun

WU Xiao-yi

TAN Zhi-gao

ZHANG Jing

WANG Chun-hua

WANG Yong

Related Institution

Zhejiang Chinese Medical University

School of Pharmacy,Shenyang Pharmaceutical University

Institute of Material Medica,Key Laboratory of Advanced Drug Delivery of Guangdong Province,Guangdong Pharmaceutical College

Foshan Fengliaoxing Pharmaceutical Co.,Ltd

School of Traditional Chinese Medicine,Capital Medical University

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰