Antioxidant Activity of Schisandrae Chinensis Fructus Red Pigment

HE Hua; LI Xian-kuan; DING Pu; SONG Xin; CHEN Ting; WANG Bing

doi:10.13422/j.cnki.syfjx.2012.18.054

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Antioxidant Activity of Schisandrae Chinensis Fructus Red Pigment

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- Antioxidant Activity of Schisandrae Chinensis Fructus Red Pigment
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 18, Pages: 140-143(2012)
- 作者机构：
  
  辽宁中医药大学药学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2012.18.054
  CLC： R285.5
- Published：2012
- 稿件说明：
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[1]何华,李先宽,丁璞,宋新,陈婷,王冰.五味子红色素抗氧化活性[J].中国实验方剂学杂志,2012,18(18):140-143.

HE Hua, LI Xian-kuan, DING Pu, et al. Antioxidant Activity of Schisandrae Chinensis Fructus Red Pigment[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 140-143.
[1]何华,李先宽,丁璞,宋新,陈婷,王冰.五味子红色素抗氧化活性[J].中国实验方剂学杂志,2012,18(18):140-143. DOI： 10.13422/j.cnki.syfjx.2012.18.054.

HE Hua, LI Xian-kuan, DING Pu, et al. Antioxidant Activity of Schisandrae Chinensis Fructus Red Pigment[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 140-143. DOI： 10.13422/j.cnki.syfjx.2012.18.054.

摘要

目的:研究五味子红色素的抗氧化作用。方法:采用紫外-可见分光光度法

以维生素C（VC）和维生素E（VE）作为阳性对照品

通过测定清除二苯代苦味酰基自由基（DPPH.）、超氧阴离子自由基（O2-.）、羟基自由基（.OH）的能力

研究五味子红色素的抗氧化活性。结果:五味子红色素清除3种自由基的EC50分别为:清除DPPH.能力（27.95 mg.L-1）、清除.OH能力（98.03 mg.L-1）、清除O2-.能力（154.270 mg.L-1）

其清除自由基能力与VC相差不大

远强于VE。结论:五味子红色素具有较强的抗氧化活性

且成明显的量效关系。

Abstract

Objective:To study on the antioxidant activity of Schisandrae Chinensis Fructus red pigment.Method:With UV-V is spectrophotometry

compared with vitamin C（VC） and vitamin E（VE）

the antioxidant activity of Schisandrae Chinensis Fructus red pigment was studied by measuring its scavenging effects on 1

1-Diphenyl-2-picrylhydrazyl radical（DPPH ·）

hydroxyl radical（· OH） and superoxide radical（O-2 ·）.Result:Antioxidant activity of Schisandrae Chinensis Fructus red pigment with EC50as index

the results were 27.95 mg · L-1（scavenging DPPH ·）

98.03 mg · L-1（scavenging · OH） and 154.27 mg · L-1（scavenging O-2 ·）.Its scavenging effects on radicals were not significant with VC

but much stronger than VE.Conclusion:Schisandrae Chinensis Fructus red pigment has strong antioxidant activity and shows a significant dose-effect relationship.

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Related Author

HE Hua

LI Xian-kuan

DING Pu

SONG Xin

Chen Ting

WANG Bing

CUI Jinpeng

GENG Xiaotong

Related Institution

Xinyang Agriculture and Forestry University

Henan Provincial Engineering Technology Research Center for Quality Control and Evaluation of Traditional Chinese Medicine， Henan University of Chinese Medicine

School of Pharmaceutical Sciences，Key Laboratory of TCM Active Ingredient，Ministry of Education，Changchun University of Chinese Medicine

School of Pharmacy， Chengdu University of Traditional Chinese Medicine（TCM）

National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines， Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences

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