Effects of Combination of Aidi Injection and Neoadjuvant Chemotherapy on Patients with Non-Small-Cell Lung Cancer and Number of CD4+CD25+ T Regulatory Cells
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Effects of Combination of Aidi Injection and Neoadjuvant Chemotherapy on Patients with Non-Small-Cell Lung Cancer and Number of CD4+CD25+ T Regulatory Cells
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 18, Pages: 291-294(2012)
TENG Yin, XIAO Jia-rong, LIN Peng, et al. Effects of Combination of Aidi Injection and Neoadjuvant Chemotherapy on Patients with Non-Small-Cell Lung Cancer and Number of CD4+CD25+ T Regulatory Cells[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 291-294.
TENG Yin, XIAO Jia-rong, LIN Peng, et al. Effects of Combination of Aidi Injection and Neoadjuvant Chemotherapy on Patients with Non-Small-Cell Lung Cancer and Number of CD4+CD25+ T Regulatory Cells[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 291-294. DOI: 10.13422/j.cnki.syfjx.2012.18.095.
Effects of Combination of Aidi Injection and Neoadjuvant Chemotherapy on Patients with Non-Small-Cell Lung Cancer and Number of CD4+CD25+ T Regulatory Cells
Objective:To explore effect of combination of Aidi injection and neoadjuvant chemotherapy on patients with non-small-cell lung cancer and number of CD4+CD25+ T regulatory cells(NSCLC).Method:Fifty patients with NSCLC were chosen for this research.Patients were divided into control group of 20 patients without application of Aidi injection and treatment group of 35 patients applied with Aidi injection.The following indexes like their short-term curative effect
operation time
blood loss in operations
ablation rate and side effects were observed;flow cytometry was used to detect and compare number of Treg before and after treatments.Result:Compared with control group
blood loss in operation was decreased significantly(615.49±114.08)mL vs.(530.15±104.55)mL(P<0.05)
curative effect increased significantly(30.00% vs 45.71%)(P<0.05)
and occurrence of leucopenia decreased significantly(60.00% vs 37.14%)(P<0.05).Number of Treg was decreased significantly after treatments for all patients(P<0.05)
which was more significant in treatment group than in control group(P<0.05).Conclusion:Combination of Aidi injection and neoadjuvant chemotherapy can enhance clinical effects on patients with NSCLC
meanwhile enhance tumor immunity and reduce side effect during the treatment.
Effects of Combination of Aidi Injection and Neoadjuvant Chemotherapy on Patients with Non-Small-Cell Lung Cancer and Number of CD4CD25 T Regulatory Cells
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Related Author
ZHANG Jian
LIN Peng
XIAO Jia-rong
TENG Yin
HUA Baojin
LI Weidong
ZHAI Haoyu
WANG Chenglei
Related Institution
Guang'anmen Hospital, China Academy of Chinese Medical Sciences
Graduate School, Shaanxi University of Chinese Medicine
Affiliated Hospital of Jiangxi University of Chinese Medicine