YUAN Hai-mei1, PENG Teng1, HUANG Dao-qiu2, et al. Chemical Constituents from the Ethyl Acetate Extract Parts of Qinzhu Siwu Tang[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(3): 136-139.
YUAN Hai-mei1, PENG Teng1, HUANG Dao-qiu2, et al. Chemical Constituents from the Ethyl Acetate Extract Parts of Qinzhu Siwu Tang[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(3): 136-139. DOI: 10.13422/j.cnki.syfjx.2013.03.053.
Chemical Constituents from the Ethyl Acetate Extract Parts of Qinzhu Siwu Tang
摘要
目的:研究芩术四物汤乙酸乙酯萃取部位的化学成分。方法:利用硅胶柱色谱和凝胶等分离操作进行分离、纯化
通过理化性质和波谱特征鉴定结构。结果:从芩术四物汤乙酸乙酯萃取部位中分离鉴定了14个化合物
分别为棕榈酸甘油酯(1)
2(S)-5
7-二羟基-6-甲氧基二氢黄酮(2)
β-谷甾醇(3)
5
7-二羟基-8-甲氧基黄酮(4)
白杨素(5)
苯甲酸(6)
白术内酯-Ⅲ(7)
反式阿魏酸(8)
7-羟基-4’-甲氧基异黄酮(9)
黄芩苷元(10)
5
7
3’
6’-四羟基-8
2’-二甲氧基黄酮(11)
3
5
7
2’
6’-五羟基二氢黄酮(12)
5
7
2’
6’-四羟基黄酮(13)
没食子酸(14)。结论:14个化合物均首次从芩术四物汤复方中分离得到。
Abstract
Objective:To study the chemical constituent from the ethyl acetate extract parts of Qinzhu Siwu Tang.Method: The compounds were isolated by column chromatography with silica gel and gel permeation chromatography.The structures were determined on the basis of physicochemical properties and spectroscopic analysis.Result: 14 compounds were isolated and identified as tripalmitin(1)
2(S)-5
7-dihydroxy-6-methoxyflavanone(2)
β-sitosterol(3)
wogonin(4)
chrysin(5)
benzoic acid(6)
atractylenolide-Ⅲ(7)
trans-ferulic acid(8)
formononetin(9)
baicalein(10)
5
7
3′
6′-tetramethoxy-8
2′-dimethoxyflavone(11)
2′
3
5
6′
7-pxy-entahydroflavanone(12)
5
7
2′
6′-tetrahy-droxy flavones(13)
gallic acid(14).Conclusion: All the compounds are isolated from Qinzhu Siwu Tang for the first time.