Objective:To discuss the effect of Psoraleae Fructus and Rehmanniae Radix on body temperature and ATPase activity in rats.Method: Fifty rats were randomly divided into the blank control group

Aconiti Lateralis Radix Praeparata control group

Rhei Radix et Rhizoma control group

psoraleae fructus group and Rehmanniae Radix group.the dosage of aconiti Lateralis Radix Praeparata control group was 6.75 g · kg-1;the dosage of Rhei Radix et Rhfizoma control group was 13.5 g · kg-1;the dosage of Psoraleae Fructus group was 4.05 g · kg-1;the dosage of Rehmanniae Radix group was 6.75 g · kg-1.The rats were fed with the amount of 10 mL · kg-1 for 28 days（the blank group was fed with equal volume of physiological saline irrigation）

1 time a day

lasting 6 days

stopping 1 day.The toe temperature and Rectal Temperature of the rats were measured 28 days after administration.The liver was removed and made into homogenate after the rats were put to death.The adenosine triphosphate（ATP） ase activity was measured.Result: The toe temperature and rectal temperature of psoraleae fructus group were obviously higher than those of blank control group（P<0.05）.The toe temperature and rectal temperature of rehmanniae radix group were obviously lower than those of blank control group（P<0.05）.The activity of Na+-K+-ATPase and Ca2+-Mg2+-ATPase in liver tissue in psoraleae fructus group were obviously higher than those in blank control group（P<0.05）.The activity of Na+-K+-ATPase and Ca2+-Mg2+-ATPase in rehmanniae radix group were obviously lower than those in blank control group（P<0.05）.Conclusion: Psoraleae fructus and rehmanniae radix have a significant influence on body temperature and ATPase activity.It is pointed that the different influences on ATPase activity of herbs with different properties might be one of the reasons why herbs with different properties could made different trends on body temperature.Its specific mechanisms should be studied further.