Components Difference in Euodia Rutaecarpa and the Processed Products Based on Fingerprint Spetrum

WEN Hui-ling1; CHENG Qi-lai1; WU Long-huo1; XIE Yi-hui2

doi:10.13422/j.cnki.syfjx.2013.05.047

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Components Difference in Euodia Rutaecarpa and the Processed Products Based on Fingerprint Spetrum

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- Components Difference in Euodia Rutaecarpa and the Processed Products Based on Fingerprint Spetrum
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 5, Pages: 76-80(2013)
- 作者机构：
  
  1. 赣南医学院
  2. 江西中医学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2013.05.047
  CLC： R284.1
- Published：2013
- 稿件说明：
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[1]温慧玲,程齐来,吴龙火,谢一辉.基于指纹图谱探讨吴茱萸不同炮制品成分的差异[J].中国实验方剂学杂志,2013,19(05):76-80.

WEN Hui-ling1, CHENG Qi-lai1, WU Long-huo1, et al. Components Difference in Euodia Rutaecarpa and the Processed Products Based on Fingerprint Spetrum[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(5): 76-80.
[1]温慧玲,程齐来,吴龙火,谢一辉.基于指纹图谱探讨吴茱萸不同炮制品成分的差异[J].中国实验方剂学杂志,2013,19(05):76-80. DOI： 10.13422/j.cnki.syfjx.2013.05.047.

WEN Hui-ling1, CHENG Qi-lai1, WU Long-huo1, et al. Components Difference in Euodia Rutaecarpa and the Processed Products Based on Fingerprint Spetrum[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(5): 76-80. DOI： 10.13422/j.cnki.syfjx.2013.05.047.

摘要

目的:探讨吴茱萸不同炮制品化学成分的差异。方法:甘草和开水作为辅料分别炮制吴茱萸

获得2个吴茱萸炮制品

并建立吴茱萸药材和吴茱萸炮制品3种样品各10批的指纹图谱

采用中药色谱指纹图谱相似度评价系统提取相关信息

用SPSS进行数据分析。结果:以10批吴茱萸生品所生成的对照图谱为参照

吴茱萸生品、甘草水泡吴茱萸及开水泡吴茱萸样品的相似度均>0.9。对30个吴茱萸样品全匹配色谱峰的聚类分析获得22个特征峰

并对此22个特征峰的峰面积进行分析

结果表明有8个特种峰经过炮制后峰面积显著性下降

另有6个特征峰经甘草水泡制后峰面积显著降低

而吴茱萸内酯及其吴茱萸碱的峰经甘草水泡制后峰面积显著性增加。结论:吴茱萸不同炮制品及吴茱萸生品的特征峰所代表的成分有显著性的差异。

Abstract

Objective:To explore the component differences of Euodia rutaecarpa and the processed products.Method: Using boiling water and licorice as auxiliary materials

two processed products were obtained.Each ten batches fingerprints of E.rutaecarpa and the processed products were established.The information of each product was extracted in traditional Chinese medicine fingerprint similarity evaluation system

and was analyzed by SPSS.Result: the similarity of E.rutaecarpa

the processed product using boiling water and the processed product using licorice were more than 0.9

compared with E.rutaecarpa as reference.With the methods of Hierarchical Cluster Analysis

22 characteristic peaks were obtained from 30 samples.And than through analyzing the 22 characteristic peak areas

the results showed that 8 characteristic peak areas decreased significantly after being prepared.Another 6 characteristic peak areas declined significantly using immersing with licorice

but the peak areas of evodiamine and limonin increased significantly.Conclusion: The difference between characteristic components of E.rutaecarpa and the processed products was significant.

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Related Institution

Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences

State Key Laboratory of Southwestern Traditional Chinese Medicine（TCM） Resources， School of Pharmacy，Chengdu University of TCM

Sichuan Neo-green Pharmaceutical Technology Development Co. Ltd.，Pengzhou

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Modern Research Center for Traditional Chinese Medicine，Shanxi University

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