LIU Wu-juan1, CHEN Qing3, WANG Qiang1, et al. Antibacterial Activity and Chemical Constituents of Petroleum Ether Fraction in Aspergillus niger Mycelia[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(5): 125-128.
LIU Wu-juan1, CHEN Qing3, WANG Qiang1, et al. Antibacterial Activity and Chemical Constituents of Petroleum Ether Fraction in Aspergillus niger Mycelia[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(5): 125-128. DOI: 10.13422/j.cnki.syfjx.2013.05.059.
Antibacterial Activity and Chemical Constituents of Petroleum Ether Fraction in Aspergillus niger Mycelia
Objective:In order to develop natural antibacterial agents
the antibacterial activity of Aspergillus niger xj was investigated.Method: The disc diffusion method was used to measure the antibacterial activity of petroleum ether(P.E)
ethyl acetate(EtOAc) and water extracts of Aspergillus niger mycelia.The P.E fraction with antibacterial activity was separated by silica gel column chromatography method
then separated and identified by GC-MS after being esterified with methanol.Result: Ten compounds were isolated and identified from the petroleum ether extract of mycelia which exhibited inhibitory effect against Staphylococcus aureus.Conclusion: The petroleum ether extract of Aspergillus niger xj mycelia contained natural substances with antibacterial activity in which fatty acids are the main constituents.
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Related Author
LIU Wu-juan
CHEN Qing
WANG Qiang
FENG Huan-peng
LI Zhu
GUO Jin
LONG Yun-chuan
Chen CHEN
Related Institution
College of Pharmaceutical Engineering of Traditional Chinese Medicine (TCM), Tianjin University of TCM
Tianjin Modern Innovation TCM Technology Co. Ltd.
Key Laboratory of Chinese Materia Medica, Key Laboratory of Basic and Application Research of Northern Medicine under Ministry of Education, Heilongjiang Key Laboratory of Traditional Chinese Medicine(TCM) and Natural Medicine Pharmacodynamic Material Bases, Heilongjiang University of Chinese Medicine
School of TCM, Guangdong Pharmaceutical University