WEI Guang-min. Clinical Research on Treatment of Qiyinliangxu Type Lung Cancer based on Renshen Yangrong Soup Combined with Chemotherapy[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(5): 312-316.
WEI Guang-min. Clinical Research on Treatment of Qiyinliangxu Type Lung Cancer based on Renshen Yangrong Soup Combined with Chemotherapy[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(5): 312-316. DOI: 10.13422/j.cnki.syfjx.2013.05.104.
Clinical Research on Treatment of Qiyinliangxu Type Lung Cancer based on Renshen Yangrong Soup Combined with Chemotherapy
Objective: To investigate the clinical efficacy of treatment on the Qiyinliangxu type lung cancer of Renshen Yangrong soup plus and minus combined with chemotherapy.Method: Sixty cases of Qiyinliangxu type lung cancer in middle and late period were randomly grouped to chemotherapy group and Renshen Yangrong soup combined with chemotherapy group
each group for 30 cases.The chemotherapy groups were only used western medicine chemotherapy scheme
and the Renshen Yangrong soup combined with chemotherapy groups were cured together with Renshen Yangrong soup based on the treatment of control group.After 3 months’ treatment continuously
the short term curative effect
the improvement of life quality
the changes of body weight
the improvement of peripheral blood and immune function
and the occurrence of adverse reaction were observed.Result: The total effectiveness of chemotherapy group and Renshen Yangrong soup combined with chemotherapy group were respectively 86.67% and 63.33%
the short term curative effect of Renshen Yangrong soup combined with chemotherapy group was better than the chemotherapy group
and there was significant difference(P<0.05);the improvement rate of life quality was respectively 60.0% and 33.3%
the Renshen Yangrong soup combined with chemotherapy group was better than the chemotherapy group
and there was significant difference(P<0.05);the improvement rate of body weight was respectively 16.67% and 13.33%
and there was no significant difference(P>0.05);the peripheral blood abnormality rates of Renshen Yangrong soup combined with chemotherapy group were obviously lower than the chemotherapy group
and there was significant difference(P<0.05);the Renshen Yangrong soup combined with chemotherapy and chemotherapy group were compared before and after treatment
the immune indexes(CD4+
CD8+
CD4+/CD8+ and the activity of NK cell) all presented significant difference of different degree(P<0.05 and P<0.01)
and the immunity of Renshen Yangrong soup combined with chemotherapy group was obviously improved;compared with chemotherapy group
the occurrence rate of adverse reaction of Renshen Yangrong soup combined with chemotherapy group was obviously lower than chemotherapy group
and there was significant difference(P<0.05).Conclusion: The Qiyinliangxu type lung cancer was cured with Renshen Yangrong soup plus and minus combined with chemotherapy
and it could effectively relieve the clinical symptoms
improve the immunity
reduce the occurrence of adverse reaction
and improve the life quality
and the TCM combined with chemotherapy had the efficacy improved and toxicity lowered
and it was worthy popularized and applied in clinic.