Clinical Research of Xingshen Tongluo Needle Medicin Improve Ischemic Stroke on Recovery Phase Neurologic Impairment

YUE Ai-xia

doi:10.13422/j.cnki.syfjx.2014100200

您当前的位置：

首页 >

文章列表页 >

Clinical Research of Xingshen Tongluo Needle Medicin Improve Ischemic Stroke on Recovery Phase Neurologic Impairment

更新时间：2024-01-04

- Clinical Research of Xingshen Tongluo Needle Medicin Improve Ischemic Stroke on Recovery Phase Neurologic Impairment
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 20, Issue 10, Pages: 200-204(2014)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2014100200
  CLC： R743.3
- Published：2014
- 稿件说明：
移动端阅览
YUE Ai-xia. Clinical Research of Xingshen Tongluo Needle Medicin Improve Ischemic Stroke on Recovery Phase Neurologic Impairment[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(10): 200-204.
DOI：

YUE Ai-xia. Clinical Research of Xingshen Tongluo Needle Medicin Improve Ischemic Stroke on Recovery Phase Neurologic Impairment[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(10): 200-204. DOI： 10.13422/j.cnki.syfjx.2014100200.

摘要

目的：观察醒神通络方加针灸对缺血性中风恢复期患者神经功能缺损的疗效及对脑血流速度及血管内皮功能的影响。方法：将84例患者采用随机数字表法分为对照组和观察组各42例。两组均按照缺血性脑卒中二级预防方案常规治疗，包括抗血小板聚集、控制血糖、控制血压，调节血脂等。观察组在对照组治疗的基础上加用醒神通络方，1剂/d，常规水煎服，同时采用醒神通络针灸治疗，3次/周。两组疗程均为8周。进行治疗前后脑卒中患者神经功能缺损程度评分（CSS评分）及日常生活能力量表（ADL）；采用经颅多普勒仪测定治疗前后脑梗死侧大脑前动脉（ACA）、大脑中动脉（MCA）、大脑后动脉（PCA）、基底动脉（BA）血流速度；检测治疗前后血清一氧化氮（NO）和内皮素1（ET-1）水平。结果：观察组疗效总有效率为83.33%，优于对照组的57.14%（P<0.05）；治疗后观察组除意识因子外，其他CSS因子评分及CSS总分均低于对照组（P<0.01）；治疗后观察组ADL评分高于对照组（P<0.01）；治疗后观察组和对照组均有改善，而治疗后的观察组ACA和MCA血流速度均较治疗前明显改善，并好于对照组（P<0.01）；两组治疗后PCA血流速度均较治疗前改善（P<0.01）；治疗后两组NO水平均升高，观察组高于对照组（P<0.01）；两组ET-1均下降，观察组低于对照组（P<0.01）。结论：醒神通络方加针灸提高缺血性中风恢复期患者ACA和MCA的血流速度，改善了血管内皮功能，改善脑血流灌注，促进了神经功能的恢复。

Abstract

Objective: The purpose is to observe curative effect of Xingshen Tongluo needle medicin improve ischemic stroke at recovery phase on neurologic impairment and its influence on cerebral blood flow speed and vascular endothelial function. Method: Eighty-four cases patients were randomly divided into control group (42 cases) and observation group (42 cases) according to digital method.Both groups were received secondary prevention plan ischemic brain death conventional cure in secondary prevention plan

including anti-platelet aggregation

blood sugar control

blood pressure control

regulating blood lipids et.Observation group took Xingshen Tongluo decoction on the basis of therapy in control group

1 does/day

conventional water frying.At the same time adopt Xingshen Tongluo acupuncture

3 times/week.Treatment courses for the two groups continued 8 weeks.Before the treatment

give a mark of nervous functional defects degree with stroke patient and record activities of daily living (ADL).Measuring arteria cerebri anterior(ACA) through transcranial doppler instrument's treatment

middle cerebral artery(MCA)

posterior cerebral artery(PCA)and basilar artery(BA) blood flow rate in cerebral infarction side.Detect the level of nitric oxide(NO) and endothelins1(ET-1). Result: The total effective rate of disease curative effect in the observation group was 83.33% superior to 57.14% of the control group(P<0.05).After treatment

except consciousness factor

in the observation group

the score of the degree of neural function defect score standard(CSS) and the total score of CSS were lower than those in the control group(P<0.01).And the score of ADL was higher than that of the control group(P<0.01)

after treatment

patients' illness in both group were improved.Besides blood velocity of ACA and MCA in observation group were better than those in the control group(P<0.01).For the two groups

compared with the time before treatment

blood velocity of PCA both improved(P<0.01).After treatment the level of NO in the two groups both increased

observation group which higher than that of the control group(P<0.01). And endothelins1 (ET-1) in the two groups both decreased

and for the observation group which lower than that of the control group(P<0.01). Conclusion: For ischemic type stroke patients

it can improve blood velocity of ACA and MCA Xingshen Tongluo needle medicine with drug was used in convalescence

and it improved function of vascular endothelium

cerebral blood perfusion

Promote the recovery of neural function.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Diagnostic Criteria of Spleen and Kidney Deficiency Syndrome in Ischemic Stroke Patients

Effect of Dingzhi Xiaowan on PI3K/Akt/mTOR/HIF-1α Pathway in Post-stroke Cognitive Impairment Model Mice

Staging Sequential Treatment of Ischemic Stroke Based on Syndrome Differentiation of Deficiency and Excess in Eight Principles

Effect of Huatan Tongluo Prescription on Vulnerability of Carotid Atherosclerotic Plaque in Hypertension

Effect of Guizhi Gegentang on Hemodynamics and Vascular Endothelial Function in Cervical Vertigo

Related Author

DONG Wenyue

LIU Xiangzhe

WANG Xinzhi

LU Yongkun

YANG Haiyan

ZHANG Han

WANG Yu

ZHONG Xiaoqin

Related Institution

The First Clinical Medical College of Henan University of Chinese Medicine

Encephalopathy Center of the First Affiliated Hospital of Henan University of Chinese Medicine

The First Affiliated Hospital of Guangzhou Medical University

Shenzhen Bao'an TCM Hospital/Bao'an TCM Hospital Affiliated to Guangzhou University of Chinese Medicine

Guangzhou University of Chinese Medicine

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰