Study on Active Ingredients for Increased Efficacy of Compatibility of Penoy and Licorice

WANG Jun; DAI Li; LI Peng-yue; HUO Hai-ru; SUI Feng; ZHANG Chun-feng; LI Lan-fang; GUO Shu-ying; LI Cang-hai; JIANG Ting-liang

doi:10.13422/j.cnki.syfjx.2014110083

您当前的位置：

首页 >

文章列表页 >

Study on Active Ingredients for Increased Efficacy of Compatibility of Penoy and Licorice

更新时间：2024-01-04

- Study on Active Ingredients for Increased Efficacy of Compatibility of Penoy and Licorice
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 20, Issue 11, Pages: 83-86(2014)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2014110083
  CLC： R289
- Published：2014
- 稿件说明：
移动端阅览
WANG Jun, DAI Li, LI Peng-yue, et al. Study on Active Ingredients for Increased Efficacy of Compatibility of Penoy and Licorice[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(11): 83-86.
DOI：

WANG Jun, DAI Li, LI Peng-yue, et al. Study on Active Ingredients for Increased Efficacy of Compatibility of Penoy and Licorice[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(11): 83-86. DOI： 10.13422/j.cnki.syfjx.2014110083.

摘要

目的：探讨芍药与甘草配伍增效的化学物质基础。方法：芍药和甘草中主要活性成分采用HPLC检测；对方法学进行了专属性、线性范围、精密度、稳定性、重复性、加样回收率等考察。结果：芍药单味药单煎后芍药苷检测到的含量为2.19 mg·g-1；甘草单味药单煎后甘草酸检测到的含量为17.13 mg·g-1；芍药和甘草分别单煎再按1：1混合，芍药苷检测到的含量为5.45 mg·g-1，甘草酸检测到的含量为17.69 mg·g-1；芍药和甘草按1：1混合煎煮，芍药苷检测到的含量为2.58 mg·g-1，甘草酸检测到的含量为18.14 mg·g-1。结论：芍药与甘草配伍，两药单煎混合芍药苷和甘草酸的含量均显著提高，但前者增高更为明显；两药混合煎煮，芍药苷和甘草酸的含量均明显提高，但以后者更为显著；芍药与甘草配伍止痛的科学基础可能与两药合用后的芍药苷和甘草酸的含量增高有关。

Abstract

Objective:To explore the chemical basis for co-application of Paeonia lactiflora and Glycyrrhizae uralensis. Method:The contents of peoniflorin and glycyrrhizin were detected by using the method of high-performance liquid chromatography (HPLC) and the test methods in terms of specificity

linear range

precision

stability

repeatability and sample recovery were performed to determine the optimum chromatographic conditions. Result:The content of peoniflorin in P. lactiflora decoction was 2.19 mg·g-1; the content of glycyrrhizin in G.uralensis was 17.13 mg·g-1; the contents of peoniflorin and glycyrrhizin were 5.45

17.69 mg·g-1 respectively when P. lactiflora and G. uralensis were mixed together after decocting the component herbs singly; the contentsof peoniflorin and glycyrrhizin were 5.45

17.69 mg·g-1 respectively when P. lactiflora and G. Uralensis were decocted together. Conclusion:The contents of peoniflorinand glycyrrhizinwere promoted significantly with the former more significant when the component herbs were decocted singly and the contents of peoniflorinand glycyrrhizin was elevated greatly with the latter more significant when the component herbs were decocted together; the increase in contents of peoniflorinand glycyrrhizin may compose one of important reasons behind the synegetic analgesic potency when P. lactiflora and G. uralensis are used together.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Phase Difference of Traditional Chinese Medicine Compound Decoction： A Review

"Compatibility" Relationship of Active Components and Heat-clearing and Blood-cooling Effect of Rehmannia glutinosa Roots

Effects of Compatibility of Ephedrae Herba，Asari Radix et Rhizoma， and Aconiti Lateralis Radix Praeparata on ILC2s-Related Factors in Lung of Allergic Rhinitis Model Mice

Pharmacological Mechanism of Huanglian Jiedutang： A Review

Compatibility Mechanism of Shangerhuang Wan in Enhancing Intestinal Motility in Rat Model of Functional Constipation by Regulating Bile Acid Metabolism

Related Author

Chao HE

Yiqiong PU

CHEN Yaman

CUI Jinpeng

ZHANG Juan

LIU Qingpu

GONG Haiyan

LEI Jingwei

Related Institution

Experiment Center of Teaching and Learning，School of Pharmacy， Shanghai University of Traditional Chinese Medicine

Henan Provincial Engineering Technology Research Center for Quality Control and Evaluation of Traditional Chinese Medicine， Henan University of Chinese Medicine

College of Agronomy， Henan Agricultural University

Beijing University of Chinese Medicine

School of Graduate Studies，Tianjin University of Traditional Chinese Medicine（TCM）

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰