Objective:To approach the applied condition of Aconiti Lateralis Radix Praeparate and Trichosanthis Fructus using together in clinical. Method:According to zhe special search condition to search the clinical literature of Aconiti Lateralis Radix Praeparate and Trichosanthis Fructus using together

then to analyze these literature from the dosage

the compatibility proportion

the dosage forms

the administration route and the processing drug conditions. Result:Altogether we have retrieved 57 satisfactory research documents on randomized controlled clinical trial of simultaneous use of monkshood and snakegourd fruit. In the combined use of the herbs with contrary natures

however

the monkshood is usually fire-grilled while the snakegourd fruit is often used in raw. In most cases

the 2 herbs are made in decoction for drink with the proportion of 1:1.For monkshood

the function of‘mild recuperation of heart and kidney Yang’is mentioned the most

and for snakegourd fruit

‘regulating the flow of Qi and relieving depression in the chest’the most. Conclusion:The literatures show that Aconiti Lateralis Radix Praeparate and Trichosanthis Fructus could be used together in clinic treatment. As a result

it was impossible to evaluate clinical effects.What's more the research was lack of adverse incidents report and theory about imcompatible herbs using together.If we want to recognition this combination' safety and effectiveness

we still need time to do more research.