Objective: To evaluate the efficacy and safety of fule cream for the theatment of infantile eczema and atopic dermatitis. Method: Fule cream was used twice a day in 71 children with eczema and atopic dermatitis. These symptom scores of erythema

edema/infiltration/papules

scratches

oozing/crusting

scaling/dry skin syndrome and lichenification were compared before and after the treatment. At the same time

the adverse events were recorded. Result: The total effective rate of the treatment in infantile eczema and atopic dermatitis was 62%. The effective rate in the children with acute eczema

subacute eczema

chronic eczema and atopic dermatitis were 68.2%

62.5%

53.3% and 61.1%

respectively. The difference for total effective rate among the four groups was not significant among three groups.SCORDA scores after the treatment were significantly lower than that before the treatment (P<0.01). Adverse reactions were transient

which had no impacts on the treatment. Conclusion: Fule cream have a promising efficacy for the treatment of infantile eczema and atopic dermatitis with a high safety.