Quality Standards Control of Quban Gels

GUO Hong-ye; KUANG Ying; YAN Xiao-ping; LIU Yu

doi:10.13422/j.cnki.syfjx.2014140045

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Quality Standards Control of Quban Gels

更新时间：2024-01-04

- Quality Standards Control of Quban Gels
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 20, Issue 14, Pages: 45-47(2014)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2014140045
  CLC： R286.0
- Published：2014
- 稿件说明：
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GUO Hong-ye, KUANG Ying, YAN Xiao-ping, et al. Quality Standards Control of Quban Gels[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(14): 45-47.
DOI：

GUO Hong-ye, KUANG Ying, YAN Xiao-ping, et al. Quality Standards Control of Quban Gels[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(14): 45-47. DOI： 10.13422/j.cnki.syfjx.2014140045.

摘要

目的：建立祛斑凝胶剂的质量标准。方法：采用TLC鉴别祛斑凝胶剂中当归、人参、茯苓，检测波长365 nm；运用HPLC测定祛斑凝胶剂中阿魏酸含量，流动相乙腈-0.085%磷酸（17：83），柱温35℃，检测波长316 nm。结果：定性鉴别中检出当归、人参、茯苓，分离度好、专属性强且阴性无干扰。阿魏酸线性范围0.024~0.144 μg，精密度RSD 0.86%，平均加样回收率100.24%（RSD 2.93%）；祛斑凝胶剂中阿魏酸平均提取量0.022 mg·g-1，RSD 1.46%。结论：建立的HPLC操作简单、重复性好，可较好地控制祛斑凝胶剂的质量，为该制剂的工业化生产提供参考。

Abstract

Objective: To establish quality standards of Quban gels. Method: TLC was adopted to identify Angelicae Sinensis Radix

Ginseng Radix et Rhizoma and Poria with detection wavelength at 365 nm.The content of ferulic acid was determined by HPLC with mobile phase consisted of acetonitrile-0.085% phosphoric acid(17:83)

column temperature was set at 35℃ and detection wavelength was 316 nm. Result: Angelicae Sinensis Radix

Ginseng Radix et Rhizoma and Poria were identified by TLC

characteristic identification had a good separation

strong specificity and no negative interference.Ferulic acid showed a good linear relationship in the range of 0.024-0.144 μg with an average recovery of 100.2%(RSD 2.93%) and precision RSD of 0.86%.Average extracting amount of ferulic acid in Quban gels was 0.022 mg·g-1 with RSD of 1.46%. Conclusion: This method could be adopted as a standard for quality control of Quban gels and provide a reference for industrial production of this preparation.

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