Objective: To discuss the hypoglycemic action of plateau plant turnip volatile oil constituents. Method: The supercritical carbon dioxide extraction was used to extract turnip volatile oil components. The animal model of diabetic mice was induced by feeding high serum glucose and serum lipid fro 4 weeks and injection of streptozotocin(100 mg·kg).The blood sugar level was detected. Forty mice whose blood glucose level was between 15-17 mmol·L-1 were randomly divided into model group

turnip volatile oil (high

low dose group)

positive control group (metformin hydrochloride)

and normal control group

altogeher 5 groups

the intragastric administration was conducted once per day for 14 days. During the experimental period

the blood glucose level was measured after 3

7

14 days of administration. After the experiment

blood samples were collected for measurements of glycosylated hemoglobin and serum insulin level.The fresh spleen and thymus gland were collected for computing organ index. Result: Turnip volatile oil components could significantly reduce blood glucose and glycosylated hemoglobin

and increase serum insulin levels. Conclusion: Turnip volatile oil components significantly reduce blood glucose.