DONG Yuan-yuan, DENG Chong, CHAI Si-jia. Adsorption Kinetics and Thermodynamics Analysis of Macroporous Resin for Total Triterpenoids in Schizandrae Sphenantherae Fructus[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(17): 5-9.
DOI:
DONG Yuan-yuan, DENG Chong, CHAI Si-jia. Adsorption Kinetics and Thermodynamics Analysis of Macroporous Resin for Total Triterpenoids in Schizandrae Sphenantherae Fructus[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(17): 5-9. DOI: 10.13422/j.cnki.syfjx.2014170005.
Adsorption Kinetics and Thermodynamics Analysis of Macroporous Resin for Total Triterpenoids in Schizandrae Sphenantherae Fructus
Objective: To investigate adsorption kinetics and thermodynamic characteristics of macroporous resin for total triterpenoids from Schizandrae Sphenantherae Fructus
in order to provide a reference for separation and purification of these compounds. Method: With adsorption and elution rate as indexes
optimum type of macroporous resin for purification of total triterpenoids was selected from 11 kinds of macroporous resin by static adsorption and desorption test
then adsorption kinetics model and adsorption isotherm model of total triterpenoids were established by AB-8 resin and calculated thermodynamic parameters. Result: AB-8 resin was selected
resin adsorption processor for total triterpenoids showed fast adsorption stage in 0-50 minutes and slow adsorption stage in 50-200 minutes
adsorption after 200 minutes was saturation stage.Adsorption dynamic behavior was well described by quasi-second-order kinetics equation
adsorption rate was mainly controlled by liquid film diffusion and intraparticle diffusion;equilibrium adsorption data were fitted Freundlich isotherm equation which was belonging to multi-molecular layer adsorption;high temperature was advantageous to adsorption. Conclusion: Adsorption process of AB-8 resin for total triterpenoids was driven by entropy
solid-liquid interface molecular motion was more confusion
more water molecules promiscuously moved from solid surface to solution
which had a certain guiding significance for optimizing purification process of total triterpenoids from Schizandrae Sphenantherae Fructus.
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Related Institution
Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine
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