SONG Xin-li, FENG Fan, ZHANG Yong-ping, et al. Effect of Jingluo Shuning Capsule Effective Parts Combinations on Blood Sugar and Glycosylated Hemoglobin in Rats[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(18): 142-146.
DOI:
SONG Xin-li, FENG Fan, ZHANG Yong-ping, et al. Effect of Jingluo Shuning Capsule Effective Parts Combinations on Blood Sugar and Glycosylated Hemoglobin in Rats[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(18): 142-146. DOI: 10.13422/j.cnki.syfjx.2014180142.
Effect of Jingluo Shuning Capsule Effective Parts Combinations on Blood Sugar and Glycosylated Hemoglobin in Rats
Objective: To study blood sugar and glycosylated hemoglobin of different doses and different compatibility of effective parts from Jingluo Shuning capsule. Method: A single intraperitoneal injection of streptozotocin (48 mg·kg-1) was used to induce diabetic rats. The modling rats were randomly divided into control group
modelgroup
Jingluo Shuning groups(34.4
68.7
137.4 mg·kg-1)and the 9 compatility groups according to the combination of three factors and three levels orthogonal design ratio. The oral administration lasted for 28 days. The fasting blood glucose levels and glycosylated hemoglobin(GHb) were measured. Result: The middle dose group had significant effect.On this basis
the different dosage group and two two compatibility were compared
the results showed the optimal dose. Finally
in the formula of the three effective parts the combination 5
indicated the best effect. Conclusion: In Jingluo Shuning effective parts combination 5 has the most significant effect on the blood sugar and GHb.