JING Wen-guang, FU Jiang, LIU Yu-mei, et al. Chemical Constituents of Hirudo[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(19): 120-123.
DOI:
JING Wen-guang, FU Jiang, LIU Yu-mei, et al. Chemical Constituents of Hirudo[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(19): 120-123. DOI: 10.13422/j.cnki.syfjx.2014190120.
separate and identify the chemical constituents from Hirudo. Method: Compounds were isolated by various chromatographic methods
and their structrues were identified by physicochemical properties and spectroscopic analysis or comparison with reference compounds. Result: From the MeOH extract of the Hirudo
eighteen compounds were isolated and identified as cholesterol (1)
hexadecyl ethers of glycerol (2)
campesterol (3)
nicotinic acid (4)
uracil (5)
uridine (6)
hypoxanthine (7)
inosine (8)
xanthine (9)
phenylalanine (10)
propylamine (11)
adenosine (12)
proline (13)
valine (14)
L-isoleucine (15)
glycerin (16)
palmiticacid(17)
and succinic acid (18). Conclusion: Compounds 4-6
8-10
12-14
16 and 17 were all obtained from the Hirudo for the first time.