YUAN Wei, ZHANG Xu, CHENG Jia-yi, et al. Comparison of Synthetic Borneol and S101 Efficacy of Rabbit Blood Pressure and Heart Rate[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(19): 167-169.
DOI:
YUAN Wei, ZHANG Xu, CHENG Jia-yi, et al. Comparison of Synthetic Borneol and S101 Efficacy of Rabbit Blood Pressure and Heart Rate[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(19): 167-169. DOI: 10.13422/j.cnki.syfjx.2014190167.
Comparison of Synthetic Borneol and S101 Efficacy of Rabbit Blood Pressure and Heart Rate
Objective: To compare the efficacy of synthetic borneol and S101 of rabbit blood pressure
heart rate and to study whether S101 can replace synthetic borneol. and provide a new medicinal resource of borneol on clinical. Method: Using RM6240 biological signal acquisition system
in which the condition is not modeling observe within 1-5 mg·kg-1 dose
diastolic blood pressure
the impact of the two drugs on systolic heart rate in normal rabbits. Result: ①Within the dose of 1-5 mg·kg-1
the efficacy of the two drugs has significantly positive correlation with dose.②At the dose of 5 mg·kg-1
synthetic borneol group and S101 group decrease systolic
diastolic blood pressure and heart rate than control group (P<0.01).S101 has lowering effect than synthetic borneol. (P<0.05
P<0.01). Conclusion: Both synthetic borneol and S101 can reduce systolic and diastolic blood pressure. slow heart rate. The effect of S101 is better than synthetic borneol. S101 has the significance of alternative synthetic borneol.