Application of Dynamic Optimization Method for Extraction Time of Arctii Fructus in Vitamin C Yinqiao Pian

ZHA Qin; YANG Shi-lin; ZHANG Jun; CHEN Sha; WANG Yue-sheng; LIU An

doi:10.13422/j.cnki.syfjx.2014210044

您当前的位置：

首页 >

文章列表页 >

Application of Dynamic Optimization Method for Extraction Time of Arctii Fructus in Vitamin C Yinqiao Pian

更新时间：2024-01-04

- Application of Dynamic Optimization Method for Extraction Time of Arctii Fructus in Vitamin C Yinqiao Pian
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 20, Issue 21, Pages: 44-46(2014)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2014210044
  CLC： R282.4;R283.6;R284.2
- Published：2014
- 稿件说明：
移动端阅览
ZHA Qin, YANG Shi-lin, ZHANG Jun, et al. Application of Dynamic Optimization Method for Extraction Time of Arctii Fructus in Vitamin C Yinqiao Pian[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(21): 44-46.
DOI：

ZHA Qin, YANG Shi-lin, ZHANG Jun, et al. Application of Dynamic Optimization Method for Extraction Time of Arctii Fructus in Vitamin C Yinqiao Pian[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(21): 44-46. DOI： 10.13422/j.cnki.syfjx.2014210044.

摘要

目的: 采用动态优化方法优选维C银翘片中牛蒡子的提取工艺。方法: 采用HPLC测定牛蒡子苷含量

检测波长280 nm

流动相乙腈-水(20:80)。通过比较动态优化工艺与原提取工艺对维C银翘片提取率、指标成分含量和指纹图谱的相似度

评价动态优化方法应用于维C银翘片中牛蒡子提取工艺优化的可行性。结果: 动态优化工艺与原提取工艺所得提取物基本一致。动态优化工艺为加8倍量60% 乙醇回流提取2次

提取时间分别为140

60 min;提取时间较原工艺节约58%

耗电量节约53%。结论: 动态优化方法可运用于维C银翘片中牛蒡子提取工艺的优化

该工艺能减少提取时间、降低能耗

具有明显的经济效益。

Abstract

Objective: To optimize extraction process of Arctii Fructus in Vitamin C Yinqiao Pian by dynamic optimization extraction method(DOEM). Method: HPLC was employed to determine the content of arctiin with detection wavelength at 280 nm and mobile phase of acetonitrile-water(20:80).Taking yield and content of arctiin

fingerprints similarity as indexes

feasibility of DOEM using in Arctii Fructus from Wei C Yinqiao tablets was evaluated

and compared with extraction process in 2010 edition of . Result: There was no difference in extract between dynamic optimization process and ordinary extraction process.Optimized DOEM was as following:reflux extracted twice with 8 times the amount of 60% ethanol for extracting time of 140 min and 60 min;it could save 58% of extraction time and 53% of power consumption. Conclusion: DOEM can be applied to optimize extraction process of Arctii Fructus in Vitamin C Yinqiao Pian

it can significantly reduce extraction time and production costs.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Extraction of Arctiin and Arctigenin from Arctii Fructus by Matrix Solid-Phase Dispersion

Application of Dynamic Optimization Method in Extraction Process Optimization of Ginseng Radix et Rhizoma

Optimization of Enrichment Process for Total Lignans from Arctii Fructus Residue After Subcritical Extraction

Content Determination of Arctiin and Arctigen from Different Parts of Arctium tomentosum by RP-HPLC

Related Author

GAO Sai-nan

DU Wen-wen

LI Chun-xiang

LI Sen

ZHEN Xi-e

JIANG Lei

CHEN Shi-tao

LU Ying-cai

Related Institution

Xinjiang Key Laboratory of Famous Prescription and Science of Formulas

College of Traditional Chinese Medicine,Xinjiang Medical University

Nanjing Children’s Hospital,Nanjing Medical University

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰