WANG Zhe. Chemical Constituents of [J]. Chinese journal of experimental traditional medical formulae, 2014, 20(21): 84-86.
DOI:
WANG Zhe. Chemical Constituents of [J]. Chinese journal of experimental traditional medical formulae, 2014, 20(21): 84-86. DOI: 10.13422/j.cnki.syfjx.2014210084.
Objective: To investigate the chemical constituents of Scutellaria barbata. Method: The compounds were isolated and purified by chromatographies on silica gel column and Sephadex LH-20 column together with recrystallization method
and their structures were elucidated on the basis of physical and spectral analyses. Result: Eight compounds were isolated and identified as p-hydroxyacetophenone (1)
p-hydroxybenzaldehyde(2)
2-hydroxy-3-methylanthraq-uinone (3)
vanillin (4)
5-hydroxy-7
3'
4'
5'-tetramethoxyflavone (5)
dihydrooroxylin A (6)
5
7
3'
4'
5'-pentamethoxyflavone (7)
hyperoside (8). Conclusion: Compounds 4
7 and 8 were obtained from Scutellaria for the first time. Compound 6 was obtained from the title plant for the first time.