Objective: To investigate influence of adjuvant therapy of Yiqi Tongguan decoction on cardiac function

quality of life

restenosis and major adverse cardiac event in patients after percutaneous coronary intervention (PCI) operation. Method: One hundred and ten patients with PCI were randomly divided into western medicine group (53 cases) and observation group (57 cases) by random number table. Patients in western medicine group received anti-coagulant medication of low molecular weight heparin for 1 week

5 mg clopidogrel hydrogen sulphate tablets once daily for 9 months

100 mg aspirin enterie ccoated tablets once daily after dinner and 80 mg simvastatin tablets once daily for 2 months after the PCI operation. Based on the treatment of western medicine group

patients in observation group added Yiqi Tongguan decoction 1 dose daily for 3 months. Patients in both groups received 12 month follow-up. The qualities of life in PCI patients were evaluated by Seattle angina questionnaire (SAQ). Echocardiogram was recorded

left ventricular ejection fraction (LVEF) and stroke volume (SV) were calculated. Heart function class was graded by New York heart association (NYHA). Major cardiovascular events of cardiac

cardiac death

unstable angina pectoris

heart failure

PCI operation and bypass were recorded. Result: Composite scores of SAQ scale of level of limitation of motion

anginal stability

seizure of stenocardia and degree of satisfaction with treatment and total scores in observation group were higher than those in western medicine group after treatment (P<0.05 or P<0.01). LVEF and SV in observation group were higher than those in western medicine group (P<0.01). Cardiac function class of NYHA in both groups ameliorated after treatment (P<0.05 or P<0.01)

and there was no statistically significant difference from two groups. Occurrence rate of restenosis in observation group was 5.26%

which is lower than that in western medicine group 11.32% with no statistically significant difference. Combined occurrence rate of cardiovascular events in observation group was 14.03%

which is lower than that in western medicine group 35.84% (P<0.01). Conclusion: Adjuvant therapy of Yiqi Tongguan decoction could improve heart function and quality of life

decrease the incidence rate of the main cardiovascular events and restenosis

improve the prognosis and promote the rehabilitation of patients with PCI.