YANG Ying-guang, ZHANG Fang, HAN Li, et al. Preliminary Exploration on Ultrafine Grinding Rules of Angelicae Dahuricae Radix Pieces[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(2): 24-26.
DOI:
YANG Ying-guang, ZHANG Fang, HAN Li, et al. Preliminary Exploration on Ultrafine Grinding Rules of Angelicae Dahuricae Radix Pieces[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(2): 24-26. DOI: 10.13422/j.cnki.syfjx.2015020024.
Preliminary Exploration on Ultrafine Grinding Rules of Angelicae Dahuricae Radix Pieces
Objective: To investigate ultrafine grinding rules of Angelicae Dahuricae Radix pieces. Method: Fine powder and ultrafine powder Ⅰ
Ⅱ
Ⅲ
Ⅳ of Angelicae Dahuricae Radix were prepared
size distribution
wettability
infrared spectrum and moisture absorption were used to evaluate these powders.HPLC was employed to determine the content of imperatorin and evaluate dissolution with methanol-water(70: 30) as mobile phase and detection wavelength at 251 nm. Result: Particle size of ordinary powder was the maximum and ultrafine powder Ⅳ was the minimum.Wettability of ordinary powder was the worst
but it improved significantly after being ultrafine ground.Wettability of ultrafine powder Ⅳ was the best and its contact angle approached zero.Infrared spectrum and moisture absorption of these five kinds of powders were extremely similar
dissolution of ultrafine powder Ⅲ was better than others. Conclusion: Chemical compositions in four kinds of ultrafine powders do not change by comparing with ordinary powder
while their micromeritic properties are difference
it shows that ultrafine grinding of herbs should choose appropriate particle size acorrding to specific application.
Application of Ultrafine Powder Solubilization Technology in Process of Canhuang Tablets
HPLC Fingerprints Integrated with Quantitative Determination of Multi-components for Quality Control of Angelicae Dahuricae Radix
Effect of Single and Mixed Decoction of Angelicae Dahuricae Radix and Myrrha on Content of Imperatorin and Their Analgesic Effect
Correlation Analysis Between Microbial Community Changes and Medicinal Quality Formation During Processing of Angelicae Dahuricae Radix
Research Progress on Pharmacological Effect and Mechanism of Imperatorin
Related Author
CHEN Hong-ge
HAN Jin
YUAN Hai-long
GAO Chun-sheng
LEI Yun
WANG Wei
SHI Yang
ZHAI Hua-qiang
Related Institution
School of Pharmacy,State Key Laboratory of Southwest Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
School of Pharmacy,Chengdu University of Traditional Chinese Medicine, State Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Medicine Resources
Key Laboratory of Modern Preparation of Traditional Chinese Medicine