YANG Bing-you, MENG Ying, LIU Zhao-xi, et al. Triterpenes from Pericarps of [J]. Chinese journal of experimental traditional medical formulae, 2015, 21(2): 49-52.
DOI:
YANG Bing-you, MENG Ying, LIU Zhao-xi, et al. Triterpenes from Pericarps of [J]. Chinese journal of experimental traditional medical formulae, 2015, 21(2): 49-52. DOI: 10.13422/j.cnki.syfjx.2015020049.
Objective: To study the anti-tumor triterpenes from the pericarps of Juglans regia. Method: The chemical constituents isolated and purified by silica gel
Sephadex LH-20 columns and recrystallization. The structures of isolated compounds were elucidated on the basis of NMR spectral data and physicochemical properties. Result: Ten compounds were separated and identified as 20(S)-protopanaxadiol(1)
20(S)-protopanaxadiol-3-one(2)
20(S)-hydroxyldammar-24-en-3-one(3)
20(S)
24(R)-dihydroxydammar-25-en-3-one(4)
1β
12β
20(S)-trihydroxydammar-24-en-3-one(5)
2α-hydroxyloleanolic acid(6)
2α
23-dihydroxyoleanolic acid(7)
2α-hydroxyursolic acid(8)
23-hydroxyursolic acid(9)
3-epikatonic acid(10). Conclusion: Compounds 1
3
and 5-10 were isolated from J.regia for the first time.
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