Influence of Fuzheng Shugan Decoction Combined Group Psychotherapy on Depression and Life Quality in Postoperative Stomach Cancer Patients

LIU Wei-wei; GU Kang-sheng

doi:10.13422/j.cnki.syfjx.2015020204

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Influence of Fuzheng Shugan Decoction Combined Group Psychotherapy on Depression and Life Quality in Postoperative Stomach Cancer Patients

更新时间：2024-01-04

- Influence of Fuzheng Shugan Decoction Combined Group Psychotherapy on Depression and Life Quality in Postoperative Stomach Cancer Patients
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 21, Issue 2, Pages: 204-208(2015)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2015020204
  CLC： R735.2
- Published：2015
- 稿件说明：
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LIU Wei-wei, GU Kang-sheng. Influence of Fuzheng Shugan Decoction Combined Group Psychotherapy on Depression and Life Quality in Postoperative Stomach Cancer Patients[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(2): 204-208.
DOI：

LIU Wei-wei, GU Kang-sheng. Influence of Fuzheng Shugan Decoction Combined Group Psychotherapy on Depression and Life Quality in Postoperative Stomach Cancer Patients[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(2): 204-208. DOI： 10.13422/j.cnki.syfjx.2015020204.

摘要

目的: 观察扶正舒肝方联合团体心理疗法对胃癌术后患者抑郁和生活质量的改善作用。方法: 将80例患者随机按住院先后分为对照组和观察组各40例。对照组根据病情选用氟西汀胶囊

20 mg ·d-1

或艾司西酞普兰片

10～20 mg/次

1次/d。观察组采用扶正舒肝方辨证内服联合团体心理疗法。两组疗程均为8周。进行治疗前后焦虑自评量表(SAS)、抑郁自评量表(SDS)、汉密尔顿抑郁量表(HAMD)、Herth希望量表(HHI)和卡氏功能状态量表(KPS)评分;生活质量表采用欧洲癌症研究与治疗组织(EORTC)的生活质量(QLQ-STO22)问卷

治疗前后各评价1次。结果: 经Ridit分析

治疗后观察组生活质量改善优于对照组(P<0.05);经Ridit分析

两组抑郁疗效比较差异无统计学意义;治疗后观察组SAS和SDS评分均低于对照组(P<0.01)

治疗后两组HAMD评分比较差异无统计学意义;治疗后对照组KPS评分下降

观察组KPS评分升高并高于对照组(P<0.01);治疗后观察组QLQ-STO22量表吞咽困难、胃疼、反流呃逆、饮食受限、焦虑、口干、味觉等维度评分低于对照组(P<0.01);治疗后观察组Herth希望量表希望总均分及对现实和未来的积极态度

采取积极的行动和与他人保持亲密的关系等3个维度评分均高于对照组(P<0.01)。结论: 扶正舒肝方联合团体心理疗法对胃癌术后患者抑郁改善作用与氟西汀胶囊等疗效相当

并能增强患者对生活的希望

稳定和提高患者的生活质量

实现较高质量的生活。

Abstract

Objective: To observe the influence of Fuzheng Shugan decoction combined group psychotherapy in treating patients with stomach cancer after therapy. Method: Eighty patients were randomly divided into control group (40 cases) and observation group (40 cases) by random number table. Patients in control group received 20 mg fluoxetine capsules and 10-20 mg escitalopram citalopram tablets once daily. Patients in observation group received Fuzheng Shugan decoction combined group psychotherapy. Patients in both groups received 8 weeks of treatment. The self-rating anxiety scale (SAS)

self-rating depression scale (SDS)

Hamilton's depression scale (HAMD)

Herth hopes list (HHI) and cartesian function scale (KPS) were scored before and after treatment. The quality of life was evaluated using QLQ-STO22 questionnaire of European organization for research and treatment of cancer (EORTC) once before and after treatment. Result: The amelioration of quality of life in observation group was superior to that in control group after treatment (P<0.05)

while there was no statistic significance difference for antidepressant action between two groups. Scores of SAS and SDS in observation group were lower than those in control group (P<0.01)

while there was no statistic significance difference for the score of HAMD in two groups. Score of KPS was decreased in control group

while it was increased and the result was higher in observation group (P<0.01). Scores of dysphagia

stomachache

reflux hiccup

constrained diet

anxiety

dry mouth and taste from QLQ-STO22 in observation group were lower than those in control group (P<0.01). Scores of the total average of hope

positive attitude to present and future and taking positive action and keeping healthy relationships with others from HHI in observation group were higher than those in control group (P<0.01). Conclusion: Fuzheng Shugan decoction combined group psychotherapy treatment has a comparative effect as compared with fluoxetine capsules in treating depression of stomach cancer after therapy. It can improve the hope of life

stabilize and improve the quality of life and realize the higher-quality life of patients.

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