TONG Rong-sheng, XIAO Kai-chun, LI Jin-qi, et al. Study on Material Basis of Banxia Xiexin Tang in Regulating Gastrointestinal Motility[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(3): 160-163.
DOI:
TONG Rong-sheng, XIAO Kai-chun, LI Jin-qi, et al. Study on Material Basis of Banxia Xiexin Tang in Regulating Gastrointestinal Motility[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(3): 160-163. DOI: 10.13422/j.cnki.syfjx.2015030160.
Study on Material Basis of Banxia Xiexin Tang in Regulating Gastrointestinal Motility
Objective: To explore the material basis of Banxia Xiexin Tang in regulating gastrointestinal motility. Method: The two kinds of model were established by subcutaneous injection of atropine sulfate and chronic water immersion stress respectively.Domperidone(0.01 g·kg-1)
Banxia Xiexin Tang(2 g·kg-1)
pungent drugs
bitter drugs and tonic with sweet drugs(1.5 g·kg-1) were orally given for 4 days. The remnant rate of stomach and progradation rate of small intestine were measured. Result: Compared with normal group
the gastric retention rate of model group increased
and the small intestinal propulsion decreased. The difference was statistically significant(P<0.05
P<0.01). When the model rats were orally given different drugs
both of the 2 indicators had different degrees of change. The banxia xiexin decoction decreased the gastric retention rate of the model rats. The ethanol precipitation of Banxia Xiexin Tang
the bitter drugs and the ethanol precipitation of bitter drugs decreased the gastric retention of normal rats and the two kinds of model rats. The difference was statistically significant (P<0.05
P<0.01). Conclusion: Banxia Xiexin Tang may be play the role of regulating gastrointestinal motility
the bitter drugs for purgation are the effective group mainly and the ethanol precipitation parts are the effective components.
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