ZHUO Shen, QIAO Xue, CHEN Jun, et al. Mechanism of Fufang Yuyang Powder on Diabetic Skin Ulcers Healing[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(4): 115-119.
DOI:
ZHUO Shen, QIAO Xue, CHEN Jun, et al. Mechanism of Fufang Yuyang Powder on Diabetic Skin Ulcers Healing[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(4): 115-119. DOI: 10.13422/j.cnki.syfjx.2015040115.
Mechanism of Fufang Yuyang Powder on Diabetic Skin Ulcers Healing
Objective: To study the mechanism of Fufang Yuyang powder on the diabetic skin ulcers healing. Method: The SD male rats were given alloxan and skin was scratched to establish the diabetic wound model. The modeling rats were randomly divided into 5 groups:model group
positive control group(Kangfuxin prescription 10.0 g · kg-1
ig)
Fufang Yuyang powder group (Fufang Yuyang powder 13.0 g · kg-1
ig)
reinforce deficiency group (Buxu prescription 5.1 g ·kg-1
ig)
removing blood stasiss group (Quyu prescription 7.9 g · kg-1
ig). enzyme linked immunosorbent assay(ELISA) was used to assay type Ⅰ and Ⅲ collagen
Smad3
Smad7
transforming groowth factor(TGF)-beta at 10
16
20 days after modeling. Result: Compared with the model group
Fufang Yuyang powder increased Ⅲ type collagen
Smad7 expression(P<0.05)
decreased Smad3 expression(P<0.05)
on the 20th day
the action was most significant
Buxu prescription increasedⅠ type collagen expression (P<0.05)
Repairing Diabetic Wounds with Polysaccharides from Traditional Chinese Medicines: A Review
Effect of Chinese Medicine on Diabetic Wound Based on Nrf2 Signaling Pathway: A Review
Effect of Kangxian Chinese Prescription on Production of Collagen Type Ⅰ and Ⅲ of Hepatic Fat Storing Cells
Experimental Study of Yiqihuoxuejiedu Decoction on Inhibiting Restenosis after Percutaneous Transluminal Angiography in Rabbits
Effect of Compound Modified Sini Powder on Expression of Type Ⅰ and Type Ⅲ Collagen in Schistosoma Japonicum-infected Mice
Related Author
Yu XIE
Jinmei ZHANG
Min ZHANG
Ting LEI
Peng LIU
Yan-ling GUO
Biao XU
Wen-jing NIU
Related Institution
The First Clinical Medical College,Shaanxi University of Chinese Medicine
Affiliated Hospital of Shaanxi University of Chinese Medicine
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine(TCM),National Clinical Research Center for Chinese Medicine Acupuncture Moxibustion
Graduate School of Tianjin University of TCM
Shandong University of Triditional Chinese Medicine