Objective: To study the effect of different combinations of herbal medicines and foods on weight loss

glucose and lipid-lowering

this is beneficial to humans and would have a broad application value. Method: Fouty-four Kunming mice were divided into the control group and different combination groups [containing different concents of α-amylase inhibitor extracted from red kidney bean

Cassiae Semen

Cratagei Fructus (Crataegus) and Radix et Rhizoma]. The body weight and organ coefficient were evaluated

the lipid

total cholesterol

and alanine aminotransferase (ALT)

aspartate aminotransferase (AST)

albumin/globulin

total protein (TP)

blood sugarg (glucose

GLU) and blood fat were tested after 30-day treatment. Result: Compared with the normal group

the body weight declined

organ coefficient changed (P<0.05

P<0.01)

the ALT

AST and TP contents reduced

albumin/globulin values raised

GLU level reduced

high-density lipoprotein raised

total cholesterol and triglyceride declined in all combination groups (P<0.05

P<0.01). Different effects on low density lipoprotein were obtained from the different combination groups (P<0.05

P<0.01). Conclusion: The experiment results showed that the α-amylase inhibitor played a significant role in reducing body weight

glucose and lipid-lowering when combined with cassia seed

hawthorn and red sage root.