Clinicai Efficacy of Bailong Lingsha Tang on Celluiar Immune Function in Patients with Advanced Non-small Cell Lung Cancer

HU Zhi-ping; GAN Ning; ZHANG Guang-shun; CHEN Huan-chao; LI Ze-hao; JIANG Jian-ping; FU Hao-yun

doi:10.13422/j.cnki.syfjx.2015040182

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Clinicai Efficacy of Bailong Lingsha Tang on Celluiar Immune Function in Patients with Advanced Non-small Cell Lung Cancer

更新时间：2024-01-04

- Clinicai Efficacy of Bailong Lingsha Tang on Celluiar Immune Function in Patients with Advanced Non-small Cell Lung Cancer
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 21, Issue 4, Pages: 182-185(2015)
- 作者机构：
- 作者简介：
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- DOI：10.13422/j.cnki.syfjx.2015040182
  CLC： R285
- Published：2015
- 稿件说明：
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HU Zhi-ping, GAN Ning, ZHANG Guang-shun, et al. Clinicai Efficacy of Bailong Lingsha Tang on Celluiar Immune Function in Patients with Advanced Non-small Cell Lung Cancer[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(4): 182-185.
DOI：

HU Zhi-ping, GAN Ning, ZHANG Guang-shun, et al. Clinicai Efficacy of Bailong Lingsha Tang on Celluiar Immune Function in Patients with Advanced Non-small Cell Lung Cancer[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(4): 182-185. DOI： 10.13422/j.cnki.syfjx.2015040182.

摘要

目的: 探讨中药白龙灵沙汤对非小细胞肺癌免疫功能的影响。方法: 观察非小细胞肺癌60例

治疗组30例

对照组30例

治疗2个周期后进行比较。结果: 与对照组比较

治疗组能够提高CD3+T细胞

CD4+T细胞百分比及CD4+/CD8+

降低CD8+T细胞百分比

提高NK细胞百分比

降低CD19+B淋巴细胞百分比。两组比较差异有显著性意义(P<0.05)。临床症状改善率治疗组为86.70%

而对照组为56.70%。两组比较差异有显著性意义(P<0.05)。治疗组与对照组相比能够显著提高行为状况评分

两组比较差异有显著性意义(P<0.05)。结论: 中药白龙灵沙汤配合化疗能改善临床症状、提高生活质量

提高机体免疫功能。

Abstract

Objective: To observe the effect of Bailong Lingsha Tang (BLLST) on cellular immune function in the treatment of advanced non-small cell lung cancer. Method: Totally 60 patients with advanced non-small cell lung cancer were randomly divided into the control group and the treatment group of 30 patients each. Patients in the control group were treated by routine chemotherapy

while patients in the treatment group were treated by combination of BLLST and routine chemotherapy. Changes of KPS and symptom scores were observed in both groups. Result: Compared with the control group

percentage levels of CD3+

CD4+

CD4+／CD8+

and NK cells increased

percentage levels of CD8+

CD19+decreased in the treatment group with significant difference (P<0.05) after 2-cycle chemotherapy. Improvement of symptoms in the treatment group (86.70%) was higher than that in the control group (56.70%) with significant difference (P<0.05). Improvement of KPS

quality of life in the treated group after treatment was superior to those in the control group with significant difference (P<0.05). Conclusion: Combination of BLLST and chemotherapy could increase the cellular immune function

improve and relax lesions symptoms

and improve the quality of life.

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