XIE Yuan, WANG Luo-lin, SHI Zhi-qi, et al. Preparation Technology of Starch Sodium Octenyl Succinate Inclusion Compound of Volatile Oil from Foeniculi Fructus[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(6): 20-24.
DOI:
XIE Yuan, WANG Luo-lin, SHI Zhi-qi, et al. Preparation Technology of Starch Sodium Octenyl Succinate Inclusion Compound of Volatile Oil from Foeniculi Fructus[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(6): 20-24. DOI: 10.13422/j.cnki.syfjx.2015060020.
Preparation Technology of Starch Sodium Octenyl Succinate Inclusion Compound of Volatile Oil from Foeniculi Fructus
Objective: To optimize preparation process of starch sodium octenyl succinate(SSOS) inclusion compound of volatile oil from Foeniculi Fructus and investigate its stability. Method: Ultrasonic cell disruption was adopted to prepare SSOS inclusion compound of volatile oil from Foeniculi Fructus
taking comprehensive score of yield of inclusion compound and inclusion rate of volatile oil as index
orthogonal test was employed to optimize inclusion process with working-interval time
total inclusion time and ratio of volatile oil from Foeniculi Fructus to SSOS as factors.Differential scanning calorimetry(DSC)
thin layer chromatography(TLC) and infrared spectroscopy(IR) were used for structure characterization of inclusion compound.Stability of inclusion compound was examined under strong light
high temperature and high humidity. Result: Optimum inclusion conditions were as follows:working time of 15 s
interval time of 20 s
total inclusion time of 12 min
ratio of volatile oil from Foeniculi Fructus to SSOS of 1:6.SSOS inclusion compound of volatile oil from Foeniculi Fructus formed successfully.Under affecting factors
the content of volatile oil in inclusion compound decreased 14.5%
19.5%-38.6% and 15.5%-30.0%
respectively. Conclusion: This optimized inclusion process was stable and feasible with high inclusion rate
it provides a reference for application of SSOS in inclusion process of volatile oil.
Progress of Historical Evolution of Processing,Chemical Compositions and Pharmacological Effects of Foeniculi Fructus
Study on Stability of Volatile Oil in Foeniculi Fructus and Screening Its Antioxidants in Accelerated Oxidation Environment
GC-MS Analysis of Effect of Different Processing Conditions on Irritation of Magnoliae OfficinalisCortex
Volatile Oil of Linderae Radix Induces Apoptosis and Autophagy of Gastric Cancer AGS Cells via AMPK/mTOR Signaling Pathway
Analysis of Quality Value Transmitting of Volatile Oil in Bran-processed Atractylodes lancea and Its Standard Decoction with Different Physicochemical Forms
Related Author
Jin-jin WANG
Qi-tong WU
Bo SHI
Ning ZHOU
Kai LI
Zhen-ling ZHANG
Jia TAI
Jun-bo ZOU
Related Institution
Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province,Henan Engineering Research Center for Special Processing Technology of Chinese Medicine,Henan University of Chinese Medicine
Key Laboratory of Modern Preparation of Traditional Chinese Medicine (TCM), Ministry of Education, Jiangxi University of TCM
Shaanxi Key Laboratory of Chinese Medicine Foundation and New Drugs Research, College of Pharmacy, Shaanxi University of Chinese Medicine
State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine
College of Pharmacy, Heilongjiang University of Chinese Medicine