ZHANG Zhen-shan, YAN Ping, TAN Zhi-bin, et al. Quality Evaluation of Medicinal Material of Zanthoxyli Radix[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(6): 57-61.
DOI:
ZHANG Zhen-shan, YAN Ping, TAN Zhi-bin, et al. Quality Evaluation of Medicinal Material of Zanthoxyli Radix[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(6): 57-61. DOI: 10.13422/j.cnki.syfjx.2015060057.
Quality Evaluation of Medicinal Material of Zanthoxyli Radix
Objective: To evaluate the quality of medicinal material of Zanthoxyli Radix in Chinese herbal medicine market. Method: The 18 batches of commercial medicinal material of Zanthoxyli Radix were identified and analysed by macroscopical identification
TLC
HPLC according to the Chinese Pharmacopoeia published in 2010.HPLC fingerprint was applied to evaluate the quality of Zanthoxyli Radix. Result: There were adulterants detected in 9 batches by the macroscopical identification
TLC and HPLC. The total ashes were between 2.4% and 6.4%
the moisture ranged from 7.0% to 12.1%
and the alcohol-soluble extract was in the range of 2.2% to 8.6%. Nitidine chloride was not be detected in 2 batches by HPLC. Compared to the HPLC fingerprint common mode of Zanthoxyli Radix
the similarity of 11 batches were less than 0.8. The 18 batches of samples were not complied with Chinese Pharmacopoeia in 2010. Conclusion: Currently
the quality of medicinal material of Zanthoxyli Radix in Chinese herbal medicine market varies greatly
and the phenomenon of adulterants doping is serious.
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Related Author
LI Wen-jing
HONG Bo
XIAO Hong-he
YAN Yan
YUE Xin-yi
CHAI Cheng-zhi
YU Bo-yang
WU Yihuan
Related Institution
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences
Modern Research Center for Traditional Chinese Medicine,Shanxi University
Hubei Meisichuang Pharmaceutical Co. Ltd.
School of Pharmacy, Henan University of Chinese Medicine
Henan Provincial Engineering Technology Research Center for Quality Control and Evaluation of Traditional Chinese Medicine, Henan University of Chinese Medicine