Objective: The purpose of this paper was to investigate the clinical efficacy of treatment on the Qiyinliangxu-type lung cancer by chemotherapy with or without Bufei Jiedu soup. Method: Seventy cases of Qiyinliangxu-type lung cancer in middle and late period were randomly grouped into chemotherapy group and Bufei Jiedu soup combined with chemotherapy group

with 35 cases in each group.The chemotherapy groups were only treated by western medicine chemotherapy scheme

while the Bufei Jiedu soup combined with chemotherapy groups were cured with Bufei Jiedu soup based on the treatment of control group.After 4 continuous treatment periods

the short-term curative effect

improvement of life quality

improvement of peripheral blood and immune function

and the occurrence of adverse reaction were examined. Result: The total effective rates in chemotherapy group and Bufei Jiedu soup combined with chemotherapy group were 85.72%and 62.86%

respectively.The short-term curative effect in Bufei Jiedu soup combined with chemotherapy group was significantly better than the chemotherapy group(P<0.05);as to the improvement of life quality

the Bufei Jiedu soup combined with chemotherapy group was significantly better than the chemotherapy group (P<0.05) with the improvement rate of life quality of 62.00% and 33.33%

respectively. The peripheral blood abnormality rates in Bufei Jiedu soup combined with chemotherapy group were significantly lower than the chemotherapy group (P<0.05);the immune indexes (CD4+

CD8+

CD4+／CD8+and the activity of NK cell) were compared before and after treatment in both Bufei Jiedu soup combined with chemotherapy group and chemotherapy group

and all showed significant difference in different degree(P<0.05)

so the immunity of Bufei Jiedu soup combined with chemotherapy group was obviously improved. Compared with chemotherapy group

the occurrence rate of adverse reaction in Bufei Jiedu soup combined with chemotherapy group was significantly lower than chemotherapy group (P<0.05). Conclusion: In the case of Qiyinliangxu-type lung cancer

the treatment of chemotherapy with or without Bufei Jiedu soup could effectively relieve the clinical symptoms

improve the immunity

reduce the occurrence of adverse reaction

and improve the life quality

and the TCM treatment combined with chemotherapy had the efficacy improved and toxicity lowered

and it was worthy of promotion and application in clinic。