XIE Yan-fu, HAN Jian-ming, DU Miao-miao, et al. Exploration of Co-fermentation System of Polygoni Multiflori Radix and Monascus[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(8): 17-20.
DOI:
XIE Yan-fu, HAN Jian-ming, DU Miao-miao, et al. Exploration of Co-fermentation System of Polygoni Multiflori Radix and Monascus[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(8): 17-20. DOI: 10.13422/j.cnki.syfjx.2015080017.
Exploration of Co-fermentation System of Polygoni Multiflori Radix and Monascus
Objective: To analyze main active compositions of drug-containing medium composed by monascus and Polygoni Multiflori Radix after fermentation and optimize its fermentation technology. Method: Qualitative and quantitative analysis were established by UV-visible full wavelength scanning method and ultraviolet spectrophotometry
based on single factor tests
with yields of monacolin K
free-anthraquinone
stilbene glucoside and combined-anthraquinone as indexes
orthogonal test was adopted to investigate effects of fermentation time
amounts of monascus and Polygoni Multiflori Radix on fermentation technology. Result: Contents of stilbene glucoside
combined-anthraquinone and total anthraquinone showed a downward trend
but free-anthraquinone showed a upward trend.Optimum fermentation conditions were as follows:Polygoni Multiflori Radix amount of 5%
fermentation temperature at 28 ℃
monascus amount of 6%
fermentation time of 7 d.Yields of stilbene glucoside
combined-anthraquinone
free-anthraquinone and monacolin K were 37.84
0.89
1.54
0.41 mg·g-1
respectively. Conclusion: Polygoni Multiflori Radix has a promoting process on growth of monascus and its secondary metabolites of monacolin K
but monascus reduces the content of combined-anthraquinone in Polygoni Multiflori Radix
which improves medicinal value of Polygoni Multiflori Radix.
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Analysis on Advantages of New Integration Processing Method in Producing Area of Polygoni Multiflori Radix Praeparata
Correlation Analysis Between Material Basis and Color Characteristics of Polygoni Multiflori Radix Decoction Pieces During Ancient Classical Nine-time Repeating Steaming and Sun-drying Processing
Herbal Textual Research on Polygoni Multiflori Radix and Polygoni Multiflori Caulis in Famous Classical Formulas
Effect of Jianchangbang Braising Method on Formation of Odor of Polygoni Multiflori Radix Based on HS-GC-MS
Related Author
ZHENG Ying
LI Wei
ZHAO Gui
HOU Ming-yue
DU Hong-zhi
WU Shan-shan
QIU Ya-lei
ZHANG Yong-mei
Related Institution
Jiangxi Jingde Traditional Chinese Medicine Co. Ltd.
School of Pharmacy, Jiangxi University of Chinese Medicine
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences
National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences
Hainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine,Hainan Branch of Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences & Peking Union Medical College