Objective: To verify that acquisition time of Leontopodium franchetii was florescence and application parts were leaf and flower by investigating content differences of total phenolic acids in L. franchetii at different harvesting time. Method: UV-Vis spectrophotometry was adopted to determine the content of total phenolic acids with chlorogenic acid as standard

Folin-phenol as chromogenic agent and detection wavelength at 765 nm. Result: Linearity range of chlorogenic acid was 0-20 mg·L-1(R2=0.999 7)

average recovery was 95.8% with RSD of 1.0%.The content of total phenolic acids from leaves of L. franchetii was up to 190.606 mg·g-1 in florescence.It showed that the content of total phenolic acids at florescence was significantly higher than other periods in L. franchetii

it in leaves and flowers were significantly higher than other plant parts. Conclusion: Total phenolic acids can be used as an evaluation index to confirm optimum acquisition time and effective parts of L. franchetii.It provides scientific basis for rational utilization and quality control of L. franchetii.