Influence of Effect and Immune Function in Children with Bronchial Asthma After Therapy of Inhaled Corticosteroid by Therapy for Yiqi Guben Tang Combined with Acupoint Sticking
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Influence of Effect and Immune Function in Children with Bronchial Asthma After Therapy of Inhaled Corticosteroid by Therapy for Yiqi Guben Tang Combined with Acupoint Sticking
Chinese Journal of Experimental Traditional Medical FormulaeVol. 21, Issue 9, Pages: 180-183(2015)
WAN Chun-xia. Influence of Effect and Immune Function in Children with Bronchial Asthma After Therapy of Inhaled Corticosteroid by Therapy for Yiqi Guben Tang Combined with Acupoint Sticking[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(9): 180-183.
DOI:
WAN Chun-xia. Influence of Effect and Immune Function in Children with Bronchial Asthma After Therapy of Inhaled Corticosteroid by Therapy for Yiqi Guben Tang Combined with Acupoint Sticking[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(9): 180-183. DOI: 10.13422/j.cnki.syfjx.2015090180.
Influence of Effect and Immune Function in Children with Bronchial Asthma After Therapy of Inhaled Corticosteroid by Therapy for Yiqi Guben Tang Combined with Acupoint Sticking
Objective: The purpose of this study was to observe the influence of effect and immune function in children with bronchial asthma after therapy of inhaled corticosteroid by treatment of Yiqi Guben Tang combined with acupoint sticking. Method: In this study
86 children with bronchial asthma from October 2012 to August 2014 were randomly divided into two groups. The control group was given therapy of inhaled corticosteroid
on the basis of control group
the observation group was given therapy of Yiqi Guben Tang combined with acupoint sticking
then clinical curative effect
the number of asthma attacks and colds
indexes of cellular immunity and humoral immunity function before and after treatment were observed. Result: After treatment of 6 months
total effective rate in observation group was 86.05%
while total effective rate in control group was 72.09%
there was no statistically significant difference between the two groups. After treatment of 12 months
total effective rate in observation group was 95.35%
total effective rate in control group was 81.40%
with no statistically significant difference between the two groups. During the treatment
asthma attack frequency in observation group was (2.8±0.3) times
that in control group was (3.1±0.4) times
there was statistically significant difference between the two groups (P <0.05);cold frequency in observation group was (2.1±0.3) times
that in control group was (3.4±0.2) times
there was statistically significant difference between the two groups (P< 0.05). Difference of CD3+
CD4+
CD8+ before treatment between the two groups had no significant difference;after treatment
CD3+ and CD4 + of both two groups were higher than before treatment
while CD8+ was lower
with significant difference (P <0.05). CD3+ and CD4+ after treatment in observation group were higher than those in control group
while CD8+ was lower
with significant difference between both groups (P <0.05). IgA
IgM
IgE
IgG and insulin-like growth factor(IGF-I) before treatment between groups had no significant difference;after treatment
IgA
IgG
IgM and IGF-I of two groups were higher than before treatment
while IgE was lower
with significant difference (P <0.05). IgA
IgG
IgM and IGF-I after treatment in observation group were higher than those in control group
while IgE was lower
with significant difference between groups (P <0.05). Conclusion: The clinical efficacy of therapy of Yiqi Guben Tang combined with acupoint sticking in the treatment of children with bronchial asthma was significant
it can alleviate clinical symptoms of asthmatic children
reduce the recurrence of asthma in children with bronchial asthma
strengthen the function of cellular immunity and humoral immunity.