Objective: To observe the clinical effect of Biyankang decoction in treating chronic rhinosinusitis (CRS) of stagnated heat of gallbladder symptom

and to investigate its influence on improving patients' quality of life. Method: One hundred and twenty patients with CRS were randomly divided into the control group (60 cases) and the observation group (60 cases). Patients in the control group received 250 mg clarithromycin granules twice daily and 15 mg·kg-1 for the children according to their weight. On the basis of nasal washing therapy in the control group

patients in the observation group added Biyankang decoction orally. All patients in two groups received 4 weeks of treatment. Then patients in two groups received half does of clarithromycin granules orally for another 8 weeks. The subjective condition was evaluated by using a visual analog scale (VAS) and the objective condition was evaluated by using the Lund-Kennedy scoring method. Nasal mucociliary transport rate (MTR) was detected by using saccharin test. The quality of life was evaluated by using sinuses nasal outcome test-20 (SNOT-20) questionnaire before and after the therapy. Result: The curative effect in the observation group was superior to that in the control group (P <0.05). The VAS

Lund-Kennedy and sign scores in the observation group were less than those in the control group (P <0.01). After treatment

nasal MTR in the observation group was higher than the control group (P <0.01). The symptoms including nasal symptoms

associated symptoms

sleep disorders and emotional end

SNOT-20 total scores in the observation group were inferior to those in the control group (P <0.01). Conclusion: Biyankang decoction could improve the subjective

objective symptoms

enhance MTR and improve the quality of life in patients with CRS of stagnated heat of gallbladder symptom. Its curative effect is superior to using western medicine treatment alone.