LIU Xi-hua, HUANG Min-qi, LIN Zhong-wen, et al. Progress in Novel Drug Delivery System of Anti-tumor Medicine-ginsenosides[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(9): 231-234.
DOI:
LIU Xi-hua, HUANG Min-qi, LIN Zhong-wen, et al. Progress in Novel Drug Delivery System of Anti-tumor Medicine-ginsenosides[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(9): 231-234. DOI: 10.13422/j.cnki.syfjx.2015090231.
Progress in Novel Drug Delivery System of Anti-tumor Medicine-ginsenosides
as the major constituent of Ginseng Radix et Rhizoma
possess significant anti-tumor effect. However
ginsenosides exhibit poor clinical bioavailability due to thelow water solubility. This paper reviewed the development and researches on novel drug delivery systems for ginsenosides in recent years
including liposomes
nanoparticles
emulsions
microspheres
etc. These drug delivery systems could endow ginsenosides improved bioavailability as well as certain controlling release or targeting capability. In addition
micelles
fibrous membranes are also employed for ginsenosides delivery. To date
ginsenosides delivery systems are not deeply developed
the trend in the future is the combination of multi-functional systems. This review may provide certain guidance or instruction for developing novel anti-tumor drug delivery systems in the future.