Objective: This research intends to study and indentify the chemical constituents of Caesalpinia minax. Method: On the basis of the regulation function of C. minax to interleukin-6(IL-6) and interleukin-8(IL-8)

which is the key factors for periodontitis. Take the refluxing extraction and gradient extraction for extraction and separation. The compounds were isolated and purified by repeated chromatography on silica gel

thin layer chromatography and recrystallization. The structures were determined by MS

NMR

and physical and chemical data analysis. Result: 8 compounds were obtained. They were identified as stigmasterol (1)

caesalmin C (2)

bonducellpin F (3)

β-sitosterol (4)

β-amyrin (5)

n-hexacosane (6)

n-triacontane (7)

simiarenol (8). Conclusion: Compounds 3 and 6-8 were isolated for the first time from C. minax. Bonducellpin F was a new cassane furanoditerpenoid. Simiarenol was triterpenoid.