Objective: The aim of this study was to observe the clinical efficacy of prostant on chronic non-bacterial prostatitis(CNP). Method: In this study

one hundred and seventy-six cases of liver depression and blood stasis patients with this disease were randomly divided into the treatment group and the control group using digital table method

with 88 cases in each group. The treatment group was given oral Qianliean pills 10 grams every time

3 times a day

while the control group was given oral Qianlie Kang tablets

5 tablets every time

3 times a day. The clinical curative effect

chronic iflammatory prostate(NIH-CPSI) score

traditional Chinese medicine(TCM) symptom score

prostate fluid parameters and urine flow rate before and after treatment were observed four weeks after treatment in the two groups. Result: After the treatment for four weeks

the total effective rate in treatment group (90.97%) was significantly higher than that in control group (68.60%) (P <0.01).The NIH-CPSI total score(9.75±3.67)

TCM symptom score(6.15±3.24)in treatment group significantly reduced compared with the control group (15.83±3.71)

(9.36±5.12)(P <0.01). In the treatment group

the prostatic fluid white blood cells and lecithin body score(0.86±0.74)

(0.75±0.63)improved significantly compared with the control group (1.54±0.37)

(1.40±0.25)(P <0.01). In treatment group

maximal urinary flow rate (MFR) and average urinary flow rate (AFR) [(22.35±4.26)

(12.35±2.24) mL·s-1] increased significantly compared with the control group[(16.54±2.73)

(10.12±2.65)mL·s-1] (P <0.01). Conclusion: Qianliean pellet can significantly decrease the NIH-CPSI score and TCM symptom score in patients with CNP

and improve the prostatic fluid parameters and urine flow rate. The clinical curative effect is remarkable.